Evidence map›Paper›PMID 25998995›Full record

ArticleNanoscale2015

Folic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy.

Zipeng Zhen, Wei Tang, Weizhong Zhang, Jin Xie

Abstract read
In one paragraph

Article in Nanoscale, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Recombinant ferritins for multimodal nanomedicine.Journal of enzyme inhibition and medicinal chemistry · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. Bioengineered Ferritin Nanocarriers for Cancer Therapy.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zipeng ZhenDepartment of Chemistry, University of Georgia, Athens, Georgia 30602, USA.
Wei Tang
Weizhong Zhang
Jin Xie

Funding

Nanoplatform-based combinational therapy against breast cancer R00CA153772 · NCI · UNIVERSITY OF GEORGIA · PI XIE, JIN · 2011 to 2013
$710k
NCI NIH HHS R00 CA153772NCI NIH HHS R00CA153772
6 · The paper itself

Abstract

We coupled folic acid as a tumour targeting ligand to the surface of ferritins and loaded them with ZnF16Pc. The resulting nanoconjugates can efficiently hone in on 4T1 tumours in vivo, and, with photoirradiation, leading to suppressed tumour growth and tumour metastasis.

Indexed as

AnimalsCell Line, TumorFerritinsFolic AcidMaterials TestingMiceMice, Inbred BALB CNanocapsulesNanoconjugatesNeoplasms, ExperimentalPhotochemotherapyPhotosensitizing AgentsTreatment OutcomeFerritinsFolic AcidNanocapsulesNanoconjugatesPhotosensitizing Agents

Identifiers

PMID25998995
PMCPMC4885642

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.