ArticleJournal of experimental botany2015
The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
- Elongator complex differentially regulates transcription and translation in the hypocotyl and cotyledons during early light-dependent Arabidopsis development.Plant & cell physiology · 2026Article
- Epigenetics and plant hormone dynamics: a functional and methodological perspective.Journal of experimental botany · 2024Review
- Transcriptomic profiling reveals histone acetylation-regulated genes involved in somatic embryogenesis in Arabidopsis thaliana.BMC genomics · 2024Article
- Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight.Biology direct · 2024Article
- The roles of epigenetic regulators in plant regeneration: Exploring patterns amidst complex conditions.Plant physiology · 2024Review
- Characterization of the Molecular Events Underlying the Establishment of Axillary Meristem Region in Pepper.International journal of molecular sciences · 2023Article
- Dynamic histone acetylation in floral volatile synthesis and emission in petunia flowers.Journal of experimental botany · 2021Article
- Epigenomic RegulatorsFrontiers in plant science · 2021Article
- Plant Elongator-Protein Complex of Diverse Activities Regulates Growth, Development, and Immune Responses.International journal of molecular sciences · 2020Review
- In silico characterization, and expression analysis of rice golden 2-like (OsGLK) members in response to low phosphorous.Molecular biology reports · 2020Article
- Epigenetic Regulation of Auxin Homeostasis.Biomolecules · 2019Review
- Discovery of novel elongator protein 2 inhibitors by compound library screening using surface plasmon resonance.RSC advances · 2019Article
- Elongator Is Required for Root Stem Cell Maintenance by RegulatingPlant physiology · 2019Article
- Comparison of the Relative Potential for Epigenetic and Genetic Variation To Contribute to Trait Stability.G3 (Bethesda, Md.) · 2018Article
- The Elongator complex-associated protein DRL1 plays a positive role in immune responses against necrotrophic fungal pathogens in Arabidopsis.Molecular plant pathology · 2018Article
- Elongator promotes germination and early post-germination growth.Plant signaling & behavior · 2018Article
- The Arabidopsis ELP3/ELO3 and ELP4/ELO1 genes enhance disease resistance in Fragaria vesca L.BMC plant biology · 2017Article
- A P-Loop NTPase Regulates Quiescent Center Cell Division and Distal Stem Cell Identity through the Regulation of ROS Homeostasis in Arabidopsis Root.PLoS genetics · 2016Article
- Emerging Trends in Epigenetic Regulation of Nutrient Deficiency Response in Plants.Molecular biotechnology · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The elongator complex subunit 2 (ELP2) protein, one subunit of an evolutionarily conserved histone acetyltransferase complex, has been shown to participate in leaf patterning, plant immune and abiotic stress responses in Arabidopsis thaliana. Here, its role in root development was explored. Compared to the wild type, the elp2 mutant exhibited an accelerated differentiation of its root stem cells and cell division was more active in its quiescent centre (QC). The key transcription factors responsible for maintaining root stem cell and QC identity, such as AP2 transcription factors PLT1 (PLETHORA1) and PLT2 (PLETHORA2), GRAS transcription factors such as SCR (SCARECROW) and SHR (SHORT ROOT) and WUSCHEL-RELATED HOMEOBOX5 transcription factor WOX5, were all strongly down-regulated in the mutant. On the other hand, expression of the G2/M transition activator CYCB1 was substantially induced in elp2. The auxin efflux transporters PIN1 and PIN2 showed decreased protein levels and PIN1 also displayed mild polarity alterations in elp2, which resulted in a reduced auxin content in the root tip. Either the acetylation or methylation level of each of these genes differed between the mutant and the wild type, suggesting that the ELP2 regulation of root development involves the epigenetic modification of a range of transcription factors and other developmental regulators.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.