Evidence map›Paper›PMID 25998904›Full record

ReviewJournal of experimental botany2015

The role of cis-zeatin-type cytokinins in plant growth regulation and mediating responses to environmental interactions.

Martin Schäfer, Christoph Brütting, Ivan David Meza-Canales, Dominik K Großkinsky, Radomira Vankova, Ian T Baldwin, Stefan Meldau

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
23.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 247 citations in OpenAlex.

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  9. RsRCO and RsLMI1 co-regulate the formation of lobed leaf in radish (Raphanus sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
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  11. Overexpression of housekeeping geneHorticulture research · 2025
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Martin SchäferDepartment of Molecular Ecology, Max-Planck-Institute for Chemical Ecology, Hans-Knöll-Str.8, 07745 Jena, Germany.
Christoph BrüttingDepartment of Molecular Ecology, Max-Planck-Institute for Chemical Ecology, Hans-Knöll-Str.8, 07745 Jena, Germany.
Ivan David Meza-CanalesDepartment of Molecular Ecology, Max-Planck-Institute for Chemical Ecology, Hans-Knöll-Str.8, 07745 Jena, Germany.
Dominik K GroßkinskyDepartment of Plant and Environmental Sciences, Copenhagen Plant Science Centre, University of Copenhagen, Højbakkegård Allé 13, 2630 Taastrup, Denmark.
Radomira VankovaLaboratory of Hormonal Regulations in Plants, Institute of Experimental Botany AS CR, v.v.i., Rozvojová 263, 165 02 Prague 6, Czech Republic.
Ian T BaldwinDepartment of Molecular Ecology, Max-Planck-Institute for Chemical Ecology, Hans-Knöll-Str.8, 07745 Jena, Germany.
Stefan MeldauKWS SAAT AG, Molecular Physiology (RD-ME-MP), Grimsehlstrasse 31, 37555 Einbeck, Germany stefan.meldau@kws.com.
Max Planck Institute for Chemical Ecology · DEMax Planck Society · DECzech Academy of Sciences, Institute of Experimental Botany · CZKWS Saat (Germany) · DEUniversity of Copenhagen · DK

Funding

European Research Council 293926
6 · The paper itself

Abstract

Cytokinins (CKs) are well-established as important phytohormonal regulators of plant growth and development. An increasing number of studies have also revealed the function of these hormones in plant responses to biotic and abiotic stresses. While the function of certain CK classes, including trans-zeatin and isopentenyladenine-type CKs, have been studied in detail, the role of cis-zeatin-type CKs (cZs) in plant development and in mediating environmental interactions is less well defined. Here we provide a comprehensive summary of the current knowledge about abundance, metabolism and activities of cZs in plants. We outline the history of their analysis and the metabolic routes comprising cZ biosynthesis and degradation. Further we provide an overview of changes in the pools of cZs during plant development and environmental interactions. We summarize studies that investigate the role of cZs in regulating plant development and defence responses to pathogen and herbivore attack and highlight their potential role as 'novel' stress-response markers. Since the functional roles of cZs remain largely based on correlative data and genetic manipulations of their biosynthesis, inactivation and degradation are few, we suggest experimental approaches using transgenic plants altered in cZ levels to further uncover their roles in plant growth and environmental interactions and their potential for crop improvement.

Indexed as

Food ChainGene Expression Regulation, PlantPlant Physiological PhenomenaHerbivoryPlant DevelopmentPlant Growth RegulatorsZeatinPlant Growth RegulatorsZeatinAbiotic stressc-io6A37-tRNAcis-zeatinherbivorypathogenplant growthprenylated tRNA.

Identifiers

PMID25998904
PMCPMC5147713
OpenAlexW2130862140

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.