Evidence map›Paper›PMID 25998379›Full record

ArticleBMC medicine2015

Electronic cigarettes and nicotine dependence: evolving products, evolving problems.

Caroline O Cobb, Peter S Hendricks, Thomas Eissenberg

Open access · goldAbstract read
In one paragraph

Article in BMC medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 50 citations in OpenAlex.

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  11. Expectancies and reasons for use of e-cigarettes among young adults: A longitudinal analysis.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
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  17. Social Profile of Middle School-Aged Adolescents Who Use Electronic Cigarettes: Implications for Primary Prevention.Prevention science : the official journal of the Society for Prevention Research · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Caroline O CobbDepartment of Psychology, Center for the Study of Tobacco Products, Virginia Commonwealth University, 1112 East Clay Street, Suite B-08, Box 980205, Richmond, VA, 23298, USA. cobbco@vcu.edu.
Peter S HendricksDepartment of Health Behavior, School of Public Health, University of Alabama at Birmingham, 227L Ryals Public Health Building, 1665 University Boulevard, Birmingham, AL, 35294, USA. phendricks@uab.edu.
Thomas EissenbergDepartment of Psychology, Center for the Study of Tobacco Products, Virginia Commonwealth University, 1112 East Clay Street, Suite B-08, Box 980205, Richmond, VA, 23298, USA. teissenb@vcu.edu.
Virginia Commonwealth University · USUniversity of Alabama at Birmingham · US

Funding

Training and Education Core p270-287P50DA036105 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EISSENBERG, THOMAS EVAN · 2013 to 2017
$19.2M
The Time Course and Clinical Significance of Early E-cigarette Withdrawal EffectsR01DA036027 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HENDRICKS, PETER S. · 2015 to 2019
$1.8M
Behavior and toxicant exposure among dual users of cigarettes and e-cigarettesR21CA184634 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI COBB, CAROLINE O · 2014 to 2015
$419k
NCI NIH HHS R21 CA184634NIDA NIH HHS P50 DA036105NIDA NIH HHS R01 DA036027
6 · The paper itself

Abstract

Electronic cigarettes (ECIGs) use an electric heater to aerosolize a liquid that usually contains propylene glycol, vegetable glycerin, flavorants, and the dependence-producing drug nicotine. ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine while some may exceed the nicotine delivery profile of a tobacco cigarette. This variability is relevant to tobacco cigarette smokers who try to switch to ECIGs. Products with very low nicotine delivery may not substitute for tobacco cigarettes, so that ECIG use is accompanied by little reduced risk of cigarette-caused disease. Products with very high nicotine delivery may make quitting ECIGs particularly difficult should users decide to try. For non-smokers, the wide variability of ECIGs on the market is especially troublesome: low nicotine products may lead them to initiate nicotine self-administration and progress to higher dosing ECIGs or other products, and those that deliver more nicotine may produce nicotine dependence where it was not otherwise present. External regulatory action, guided by strong science, may be required to ensure that population-level nicotine dependence does not rise.

Indexed as

Tobacco Use DisorderElectronic Nicotine Delivery SystemsHumansNicotineRisk Reduction BehaviorNicotine

Identifiers

PMID25998379
PMCPMC4440602
OpenAlexW1481550566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.