Evidence map›Paper›PMID 25997949›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2015

Effect of knee angle on quadriceps strength and activation after anterior cruciate ligament reconstruction.

Chandramouli Krishnan, Paul Theuerkauf

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chandramouli KrishnanDepartment of Physical Medicine and Rehabilitation, University of Michigan Medical School, Ann Arbor, Michigan; School of Kinesiology, University of Michigan, Ann Arbor, Michigan; and Deparment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan mouli@umich.edu.
Paul TheuerkaufDepartment of Physical Medicine and Rehabilitation, University of Michigan Medical School, Ann Arbor, Michigan;

Funding

NRI: Wearable eMbots to Induce Recovery of FunctionR01EB019834 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DURFEE, WILLIAM K, GILLESPIE, RICHARD BRENT · 2014 to 2016
$854k
NIBIB NIH HHS R01-EB019834
6 · The paper itself

Abstract

Quadriceps strength and activation deficits after anterior cruciate ligament (ACL) injury or surgery are typically evaluated at joint positions that are biomechanically advantageous to the quadriceps muscle. However, the effect of knee joint position and the associated changes in muscle length on strength and activation is currently unknown in this population. Here, we examined the effect of knee angle on quadriceps strength, activation, and electrically evoked torque in individuals with ACL reconstruction. Furthermore, we evaluated whether knee angle mediated the relationship between quadriceps weakness and functional performance after ACL reconstruction. Knee strength and activation were tested bilaterally at 90° and 45° of knee flexion in 11 subjects with ACL reconstruction using an interpolated triplet technique. The magnitude of electrically evoked torque at rest was used to quantify peripheral muscle contractile property changes, and the single-leg hop for distance test was used to evaluate functional performance. The results indicated that although quadriceps strength deficits were similar between knee angles, voluntary activation deficits were significantly higher in the reconstructed leg at 45° of knee flexion. On the contrary, the side-to-side evoked torque at rest ratio [i.e., (reconstructed/nonreconstructed) × 100] was significantly lower at 90° than at 45° of knee flexion. The association between quadriceps strength and functional performance was stronger at 45° of knee flexion. The results provide novel evidence that quadriceps activation is selectively affected at 45° of knee flexion and emphasize the importance of assessing quadriceps strength and activation at this position when feasible because it better captures activation deficits.

Indexed as

Anterior Cruciate Ligament ReconstructionMuscle StrengthRange of Motion, ArticularAdultAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesFemaleHumansMaleMiddle AgedMuscle, SkeletalPostureTreatment OutcomeYoung Adultcentral activationinhibitionmuscle weaknessrehabilitationtwitch interpolation

Identifiers

PMID25997949
PMCPMC4526702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.