Evidence map›Paper›PMID 25997937›Full record

ArticleeLife2015

Closing the Mad2 cycle.

Andrea Musacchio

Abstract readComment
In one paragraph

Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Andrea MusacchioDepartment of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany and the Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosome separation is regulated by a cycle that involves a protein undergoing an unusual topological conversion.

Indexed as

Adenosine TriphosphatasesAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsHumansMad2 ProteinsSpindle ApparatusAdenosine TriphosphatasesCaenorhabditis elegans ProteinsCell Cycle ProteinsMad2 ProteinsAAA+ ATPasebiochemistrybiophysicsC. eleganscheckpoint proteinsHORMA domain proteinMad2mousespindle assembly checkpointstructural biology

Identifiers

PMID25997937
PMCPMC4439612

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.