ReviewDevelopment and psychopathology2015
Early life nutrition and neural plasticity.
Review in Development and psychopathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Do Vegetarian Diets Provide Adequate Nutrient Intake during Complementary Feeding? A Systematic Review.Nutrients · 2022Pooled it
- Omega-3 Fatty Acid Dietary Supplements Consumed During Pregnancy and Lactation and Child Neurodevelopment: A Systematic Review.The Journal of nutrition · 2021Pooled it
- Food Insecurity and Child Development: A State-of-the-Art Review.International journal of environmental research and public health · 2021Pooled it
- Association between parental body mass index and autism spectrum disorder: a systematic review and meta-analysis.European child & adolescent psychiatry · 2019Pooled it
- Young adult outcomes associated with lower cognitive functioning in childhood related to iron-fortified formula in infancy.Nutritional neuroscience · 2022Trial
- Effect of Delayed Cord Clamping on Neurodevelopment at 3 Years: A Randomized Controlled Trial.Neonatology · 2021Trial
- Timing, duration, and severity of iron deficiency in early development and motor outcomes at 9 months.European journal of clinical nutrition · 2018Trial
- Iron Supplementation in Pregnancy or Infancy and Motor Development: A Randomized Controlled Trial.Pediatrics · 2016Trial
- Type and developmental timing of childhood adversity predicts psychopathology symptoms in a South African birth cohort.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Long-term neuronal and neurocognitive consequences in offspring after prenatal exposure to a novel antidepressant, vilazodone: Role of BDNF/Bax-Bcl-2/AChE mediated pathways.Psychopharmacology · 2026Article
- PICU associated social-emotional adversity in early childhood cancer patients: consequences in neurodevelopment and mental health.Frontiers in oncology · 2026Review
- Bioactive compounds and exercise in aging and neurodegeneration: mechanistic insights from the gut-brain-metabolic axis.Frontiers in nutrition · 2026Review
- 2020-2025 Dietary Guidelines for Americans in Pregnancy: Adherence Shortfalls and Associations with Gestational Weight Gain.The Journal of nutrition · 2026Article
- Resilience and brain health in global populations.Nature medicine · 2025Review
- Maternal iron deficiency assessed by serum ferritin and birth outcomes in mainland China.Scientific reports · 2025Article
- Prospective associations of infant food exposures and appetitive traits with early childhood diet quality.The international journal of behavioral nutrition and physical activity · 2024Article
- Astaxanthin and DHA Supplementation Modulates the Maternal Undernutrition-induced Impairment of Cognitive Behavior and Synaptic Plasticity in Adult Life of Offspring's -Exploring the Molecular Mechanism.Molecular neurobiology · 2024Article
- Article
- Preventing Childhood Neurodisability.The Malaysian journal of medical sciences : MJMS · 2024Article
- Obesogenic diet in pregnancy disrupts placental iron handling and ferroptosis and stress signalling in association with fetal growth alterations.Cellular and molecular life sciences : CMLS · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The human brain undergoes a remarkable transformation during fetal life and the first postnatal years from a relatively undifferentiated but pluripotent organ to a highly specified and organized one. The outcome of this developmental maturation is highly dependent on a sequence of environmental exposures that can have either positive or negative influences on the ultimate plasticity of the adult brain. Many environmental exposures are beyond the control of the individual, but nutrition is not. An ever-increasing amount of research demonstrates not only that nutrition shapes the brain and affects its function during development but also that several nutrients early in life have profound and long-lasting effects on the brain. Nutrients have been shown to alter opening and closing of critical and sensitive periods of particular brain regions. This paper discusses the roles that various nutrients play in shaping the developing brain, concentrating specifically on recently explicated biological mechanisms by which particularly salient nutrients influence childhood and adult neural plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.