ArticleScandinavian journal of gastroenterology2015
Clinical characteristics and patterns and predictors of response to therapy in collagenous and lymphocytic colitis.
Article in Scandinavian journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03063957 (Identification and Characterization of Microbial and Immunologic Changes in Microscopic Colitis), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identification and Characterization of Microbial and Immunologic Changes in Microscopic Colitis
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pooled it
- Clinical Characteristics and Treatment Response in Microscopic Colitis Based on Age at Diagnosis: A Multicenter Retrospective Study.Digestive diseases and sciences · 2022Article
- European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations.United European gastroenterology journal · 2021Article
- Is There a Role for Bismuth in Diarrhea Management?Rambam Maimonides medical journal · 2021Review
- Bismuth Toxicity Presenting as Declining Mobility and Falls.Canadian geriatrics journal : CGJ · 2018Article
- Current Approach to the Evaluation and Management of Microscopic Colitis.Current gastroenterology reports · 2017Review
- Diagnosis and Management of Microscopic Colitis.The American journal of gastroenterology · 2017Review
- Diagnosis and treatment of microscopic colitis.Clinical journal of gastroenterology · 2016Review
- Prevalence and Risk Factors of Gestational Diabetes in Iran: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundCollagenous colitis (CC) and lymphocytic colitis (LC) are chronic inflammatory disorders of the colon. There is a paucity of data on differences in etiology, natural history, and treatment response between CC and LC.
methodsBetween 2002 and 2013, we identified new diagnoses of CC and LC using the Research Patient Data Registry in a tertiary referral center. We used chi square or Fischer's exact test and Wilcoxon rank-sum tests to compare the differences in clinical characteristics, treatment types, and response rates between LC and CC.
resultsThrough 2013, we confirmed 131 patients with a new diagnosis of microscopic colitis (MC) (55 LC, 76 CC). Compared to cases of LC, patients with a diagnosis of CC were more likely to be women (86% vs. 69%, p = 0.03), have elevated erythrocyte sedimentation rate (mean 28 vs. 13 mm/h, p = 0.04), and less likely to be diabetic (5% vs. 18%, p = 0.02). Budesonide was the most effective treatment for both CC and LC (94% and 80%, respectively). However, there were no statistically significant differences in response to various treatments according to the type of MC (all p > 0.10). Older age at the time of diagnosis was associated with better response to bismuth subsalicylate (odds ratio: 1.76; 95% confidence interval: 1.21-2.56 for every 5-year increase) for both CC and LC.
conclusionDespite differences in the clinical characteristics, response rates to available treatments appeared to be similar in both LC and CC. Older patients may have a better response to bismuth subsalicylate therapy.
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Registered trials
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