ArticleMethods in cell biology2015
Reconstituting SNARE-mediated membrane fusion at the single liposome level.
Article in Methods in cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Munc18 binds to and organizes membrane-bound acceptor Q-SNARE complexes in a fashion that depends on the membrane's lipid composition.bioRxiv : the preprint server for biology · 2026Article
- How SNARE proteins generate force to fuse membranes.Biophysical journal · 2025Article
- A practical guide for fast implementation of SNARE-mediated liposome fusion.Biophysics reports · 2024Article
- Malaria parasites release vesicle subpopulations with signatures of different destinations.EMBO reports · 2022Article
- A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics.Journal of visualized experiments : JoVE · 2020Article
- Mouse TMCO5 is localized to the manchette microtubules involved in vesicle transfer in the elongating spermatids.PloS one · 2019Article
- Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability.Biophysical journal · 2017Article
- Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion.Biophysical journal · 2017Article
- Reconstitution of calcium-mediated exocytosis of dense-core vesicles.Science advances · 2017Article
- HIV virions sense plasma membrane heterogeneity for cell entry.Science advances · 2017Article
- Planar Supported Membranes with Mobile SNARE Proteins and Quantitative Fluorescence Microscopy Assays to Study Synaptic Vesicle Fusion.Frontiers in molecular neuroscience · 2017Review
- Assembly and Comparison of Plasma Membrane SNARE Acceptor Complexes.Biophysical journal · 2016Article
- High cholesterol obviates a prolonged hemifusion intermediate in fast SNARE-mediated membrane fusion.Biophysical journal · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Successful reconstitutions of SNARE-mediated intracellular membrane fusion have been achieved in bulk fusion assays since 1998 and in single liposome fusion assays since 2004. Especially in neuronal presynaptic SNARE-mediated exocytosis, fusion is controlled by numerous accessory proteins, of which some functions have also been reconstituted in vitro. The development of and results obtained with two fundamentally different single liposome fusion assays, namely liposome-to-supported membrane and liposome-to-liposome, are reviewed. Both assays distinguish between liposome docking and fusion steps of the overall fusion reaction and both assays are capable of resolving hemi-and full-fusion intermediates and end states. They have opened new windows for elucidating the mechanisms of these fundamentally important cellular reactions with unprecedented time and molecular resolution. Although many of the molecular actors in this process have been discovered, we have only scratched the surface of looking at their fascinating plays, interactions, and choreographies that lead to vesicle traffic as well as neurotransmitter and hormone release in the cell.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.