Evidence map›Paper›PMID 25997066›Full record

ArticleMedicine2015

18F-FDG PET/CT role in staging of gastric carcinomas: comparison with conventional contrast enhancement computed tomography.

Corinna Altini, Artor Niccoli Asabella, Alessandra Di Palo, Margherita Fanelli, Cristina Ferrari, Marco Moschetta, Giuseppe Rubini

Abstract readComparative Study
In one paragraph

Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Improving MR sequence of 18F-FDG PET/MR for diagnosing and staging gastric Cancer: a comparison study toCancer imaging : the official publication of the International Cancer Imaging Society · 2020
    Article
  8. Metabolic Characteristics and Diagnostic Contribution ofMolecular imaging and radionuclide therapy · 2020
    Article
  9. Annals of nuclear medicine · 2020
    Article
  10. Article
  11. Article
  12. Investigation of Association Between Borderline Pancreatic Head Cancer and Glucose Uptake by Using Positron-Emission Tomographic Studies.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  13. Comparison of DWI andOncotarget · 2017
    Article
  14. Article
  15. Review
  16. Article
  17. BMC medical imaging · 2016
    Article
  18. Article
  19. Article
  20. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in a rare case of carcinoma stomach with concomitant silicosis.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Corinna AltiniFrom the Nuclear Medicine Unit (CA, ANA, ADP, MF, CF, GR); Section of Diagnostic Imaging, D.I.M., University of Bari "Aldo Moro", Bari, Italy (MM).
Artor Niccoli Asabella
Alessandra Di Palo
Margherita Fanelli
Cristina Ferrari
Marco Moschetta
Giuseppe Rubini

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the report was to evaluate the role of fluorine-18 fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT) in staging gastric cancer comparing it with contrast enhancement computed tomography (CECT).This retrospective study included 45 patients who underwent performed whole body CECT and F-FDG PET/CT before any treatment. We calculated CECT and F-FDG PET/CT sensitivity, specificity, accuracy, positive and negative predictive values (PPV and NPV) for gastric, lymphnode, and distant localizations; furthermore, we compared the 2 techniques by McNemar test. The role of F-FDG PET/CT semiquantitative parameters in relation to histotype, grading, and site of gastric lesions were evaluated by ANOVA test.Sensitivity, specificity, accuracy, PPV and NPV of CECT, and F-FDG PET/CT for gastric lesion were, respectively, 92.11%, 57.14%, 86.66%, 92.11%, 57.14% and 81.58%, 85.71%, 82.22%, 96.88%, 46.15%. No differences were identified between the 2 techniques about sensitivity and specificity. No statistical differences were observed between PET parameters and histotype, grading, and site of gastric lesion. The results of CECT and F-FDG PET/CT about lymphnode involvement were 70.83%, 61.90%, 66.66%, 68%, 65% and 58.33%, 95.24%, 75.55%, 93.33%, 66.67%. The results of CECT and F-FDG PET/CT about distant metastases were 80%, 62.86%, 66.66%, 38.10%, 91.67% and 60%, 88.57%, 82.22%, 60%, 88.57%. FDG PET/CT specificity was significantly higher both for lymphnode and distant metastases.The F-FDG PET/CT is a useful tool for the evaluation of gastric carcinoma to detect primary lesion, lymphnode, and distant metastases using 1 single image whole-body technique. Integration of CECT with F-FDG PET/CT permits a more valid staging in these patients.

Indexed as

AdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18HumansLymphatic MetastasisMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingPositron-Emission TomographyReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityStomachFluorodeoxyglucose F18

Identifiers

PMID25997066
PMCPMC4602890

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.