Evidence map›Paper›PMID 25997039›Full record

ArticleMedicine2015

Cadmium status among pediatric cancer patients in Egypt.

Laila M Sherief, Elhamy R Abdelkhalek, Amal F Gharieb, Hanan S Sherbiny, Doaa M Usef, Mohamed A A Almalky, Naglaa M Kamal, Mostafa A Salama, Wafaa Gohar

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Developmental toxicity of cadmium in infants and children: a review.Environmental analysis, health and toxicology · 2021
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Laila M SheriefFrom the Department of Pediatrics, Faculty of Medicine, Zagazig (LMS, ERA, HSS, DMU, MAAA, WG); Cairo (NMK); Benha Universities (MAS); Benha children Hospital, Benha (LMS, ERA, MAS); and Department of Biochemistry, Zagazig University, Zagazig, Egypt (AFG).
Elhamy R Abdelkhalek
Amal F Gharieb
Hanan S Sherbiny
Doaa M Usef
Mohamed A A Almalky
Naglaa M Kamal
Mostafa A Salama
Wafaa Gohar
Creative Commons · USBenha University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is a toxic, nonessential, and bio-accumulating heavy metal widely used in industry. Several studies have suggested a positive association between Cd exposure and risks of several cancers. However, data from general population, especially children are sparse.In the current cross-sectional case-control study, we aimed to assess the association between Cd exposure, as expressed by Cd body status (blood, urine, scalp hair, and nails) and cancer among Egyptian children. Three hundred and fifty pediatric cancer cases aged 3 to 14-years old were enrolled in our study. Their body Cd levels were evaluated using Atomic Absorption Spectrophometer and were compared with Cd levels of 350 healthy children.Significantly higher Cd levels (blood, urine, scalp hair, and nails) were documented in cancer cases when compared with control (P < 0.001). Such difference was still detected when comparing each malignant type separately, with controls. Tobacco smoke exposure, rural residence, and low socioeconomic status were reported more frequently among cases than comparisons.Positive association between Cd exposure and pediatric malignancy may be present.

Indexed as

AdolescentCadmiumCadmium PoisoningCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesEgyptFemaleHairHumansMaleNailsNeoplasmsSocioeconomic FactorsSpectrophotometry, AtomicCadmium

Identifiers

PMID25997039
PMCPMC4602885
OpenAlexW2313709041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.