ArticlePloS one2015
Hybrid breakdown in cichlid fish.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evolutionary dynamics of pre- and postzygotic reproductive isolation in cichlid fishes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Pooled it
- Reduced Offspring Viability Is Associated With Long-Term Stability of a Narrow Avian Hybrid Zone.Ecology and evolution · 2025Article
- Article
- Article
- Transcriptome Profile Analyses of Head Kidney in Roach (Biology · 2023Article
- Hybrid breakdown in male reproduction between recently diverged Drosophila melanogaster populations has a complex and variable genetic architecture.Evolution; international journal of organic evolution · 2023Article
- Monogeneans in intergeneric hybrids of leuciscid fish: Is parasite infection driven by hybrid heterosis, genetic incompatibilities, or host-parasite coevolutionary interactions?Frontiers in zoology · 2023Article
- Modelling speciation: Problems and implications.In silico biology · 2023Article
- Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother's Curse.Genes · 2022Review
- Three problems in the genetics of speciation by selection.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Hybrid fitness effects modify fixation probabilities of introgressed alleles.G3 (Bethesda, Md.) · 2022Article
- The Reproductive Success ofAnimals : an open access journal from MDPI · 2022Article
- Article
- Stable species boundaries despite ten million years of hybridization in tropical eels.Nature communications · 2020Article
- Assessing the fitness consequences of mitonuclear interactions in natural populations.Biological reviews of the Cambridge Philosophical Society · 2019Article
- Understanding explosive diversification through cichlid fish genomics.Nature reviews. Genetics · 2018Review
- Genomic DNA variation confirmed Seriola lalandi comprises three different populations in the Pacific, but with recent divergence.Scientific reports · 2017Article
- Cytoplasmic-Nuclear Incompatibility Between Wild Isolates ofG3 (Bethesda, Md.) · 2017Article
- Ancient hybridization fuels rapid cichlid fish adaptive radiations.Nature communications · 2017Article
- Mechanical Transgressive Segregation and the Rapid Origin of Trophic Novelty.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies from a wide diversity of taxa have shown a negative relationship between genetic compatibility and the divergence time of hybridizing genomes. Theory predicts the main breakdown of fitness to happen after the F1 hybrid generation, when heterosis subsides and recessive allelic (Dobzhansky-Muller) incompatibilities are increasingly unmasked. We measured the fitness of F2 hybrids of African haplochromine cichlid fish bred from species pairs spanning several thousand to several million years divergence time. F2 hybrids consistently showed the lowest viability compared to F1 hybrids and non-hybrid crosses (crosses within the grandparental species), in agreement with hybrid breakdown. Especially the short- and long-term survival (2 weeks to 6 months) of F2 hybrids was significantly reduced. Overall, F2 hybrids showed a fitness reduction of 21% compared to F1 hybrids, and a reduction of 43% compared to the grandparental, non-hybrid crosses. We further observed a decrease of F2 hybrid viability with the genetic distance between grandparental lineages, suggesting an important role for negative epistatic interactions in cichlid fish postzygotic isolation. The estimated time window for successful production of F2 hybrids resulting from our data is consistent with the estimated divergence time between the multiple ancestral lineages that presumably hybridized in three major adaptive radiations of African cichlids.
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