Evidence map›Paper›PMID 25996313›Full record

ReviewThe Analyst2015

Mass spectrometry tools and workflows for revealing microbial chemistry.

Tal Luzzatto-Knaan, Alexey V Melnik, Pieter C Dorrestein

Abstract readReview
In one paragraph

Review in The Analyst, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Advances in Mass Spectrometry-Metabolomics Based Approaches.Advances in experimental medicine and biology · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Natural products chemistry: The emerging trends and prospective goals.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2018
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Natural products from microbes associated with insects.Beilstein journal of organic chemistry · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tal Luzzatto-KnaanCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, USA. pdorrestein@ucsd.edu.
Alexey V Melnik
Pieter C Dorrestein

Funding

Unified Computation Tools for Natural Products ResearchR01GM107550 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COTTRELL, GARRISON W, GERWICK, WILLIAM HENRY · 2013 to 2025
$8.2M
The chemical and genetic basis of interspecies interactionsR01AI095125 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DORRESTEIN, PIETER C, POGLIANO, KIT J · 2011 to 2014
$2.4M
Experiment based genome mining of ribosomal natural productsR01GM097509 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DORRESTEIN, PIETER C, MOORE, BRADLEY S · 2012 to 2015
$1.9M
Real-Time Imaging of metabolic CommunicationR01GM094802 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DORRESTEIN, PIETER C · 2010 to 2013
$1.0M
Synapt ion mobility mass spectrometerS10RR029121 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DORRESTEIN, PIETER C · 2011 to 2011
$802k
NCRR NIH HHS S10 RR029121NCRR NIH HHS S10RR029121NIAID NIH HHS AI095125NIAID NIH HHS R01 AI095125NIGMS NIH HHS GM094802NIGMS NIH HHS GM097509NIGMS NIH HHS GM107550NIGMS NIH HHS R01 GM094802NIGMS NIH HHS R01 GM097509NIGMS NIH HHS R01 GM107550
6 · The paper itself

Abstract

Since the time Van Leeuwenhoek was able to observe microbes through a microscope, an innovation that led to the birth of the field of microbiology, we have aimed to understand how microorganisms function, interact and communicate. The exciting progress in the development of analytical technologies and workflows has demonstrated that mass spectrometry is a very powerful technique for the interrogation of microbiology at the molecular level. In this review, we aim to highlight the available and emerging tools in mass spectrometry for microbial analysis by overviewing the methods and workflow advances for taxonomic identification, microbial interaction, dereplication and drug discovery. We emphasize their potential for future development and point out unsolved problems and future directions that would aid in the analysis of the chemistry produced by microbes.

Indexed as

BacteriaBacterial InfectionsBacterial Physiological PhenomenaDrug DiscoveryEquipment DesignFungiHumansMass SpectrometryMicrobial InteractionsMycosesWorkflow

Identifiers

PMID25996313
PMCPMC5444374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.