Evidence map›Paper›PMID 25996081›Full record

ReviewThe FEBS journal2015

Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription.

Eulàlia de Nadal, Francesc Posas

Abstract readReview
In one paragraph

Review in The FEBS journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Surprising regulatory plasticity for the conserved HOG pathway in diversebioRxiv : the preprint server for biology · 2025
    Article
  2. Article
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  4. Review
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  8. Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases.International journal of molecular sciences · 2022
    Article
  9. Cip1 tunes cell cycle arrest duration upon calcineurin activation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
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  13. Rapid and reversible cell volume changes in response to osmotic stress in yeast.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  14. Genetic Interactions BetweenFrontiers in fungal biology · 2021
    Article
  15. Hog1 Controls Lipids Homeostasis Upon Osmotic Stress inJournal of fungi (Basel, Switzerland) · 2020
    Article
  16. Review
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  19. Context-Specific Nested Effects Models.Journal of computational biology : a journal of computational molecular cell biology · 2020
    Article
  20. Characterization of genes responsive to osmotic and oxidative stresses of the sugarcane bacterial pathogen Leifsonia xyli subsp. xyli.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eulàlia de NadalCell Signaling Unit, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
Francesc PosasCell Signaling Unit, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden changes in the environment. Several aspects of cell physiology change during adaptation. Major changes in gene expression are associated with cell exposure to environmental changes, and several aspects of mRNA biogenesis appear to be targeted by signaling pathways upon stress. Exhaustive reviews have been written regarding adaptation to stress and regulation of gene expression. In this review, using osmostress in yeast as a prototypical case study, we highlight those aspects of regulation of gene induction that are general to various environmental stresses as well as mechanistic aspects that are potentially conserved from yeast to mammals.

Indexed as

Gene Expression Regulation, FungalOsmotic PressureTranscription, GeneticAdaptation, PhysiologicalAnimalsCell CycleChromatin Assembly and DisassemblyMitogen-Activated Protein KinasesRNA, Long NoncodingRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionStress, PhysiologicalHOG1 protein, S cerevisiaeMitogen-Activated Protein KinasesRNA, Long NoncodingRNA, MessengerSaccharomyces cerevisiae Proteinsgene expressionHog1mammalsosmostressp38SAPKstress responsesyeast

Identifiers

PMID25996081
PMCPMC4744689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.