ReviewThe Korean journal of internal medicine2015
Hard tissue regeneration using bone substitutes: an update on innovations in materials.
Review in The Korean journal of internal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Applications of Bacterial Cellulose-Based Composite Materials in Hard Tissue Regenerative Medicine.Tissue engineering and regenerative medicine · 2023Pooled it
- Immunological Evaluation of PLLA/GO Scaffolds in Goat Mandibular Bone Regeneration.Macromolecular bioscience · 2026Article
- Corrigendum to "Strong living scaffolds for load-bearing musculoskeletal tissue regeneration" [Mater. Today Bio 35 (2025) 102571].Materials today. Bio · 2026Article
- A pre-market, open-label, single-arm study to evaluate b.Bone for posterolateral fusion treatment of degenerative thoracolumbar, lumbar or lumbosacral spinal disease (b.Spine clinical trial).Frontiers in bioengineering and biotechnology · 2026Article
- Assessment of the Osseointegration of Pure-Phase β-Tricalcium Phosphate (β-TCP) Ceramic Cylinder Implants in Critical Segmental Radial Bone Defects in Rabbits.Veterinary sciences · 2025Article
- Research Progress of Magnesium Alloys and Its Alloys in Medical Applications.International journal of general medicine · 2025Review
- Surface modification of activated carbon cloth with calcium silicate and hydroxyapatite: bioactive composite material.Heliyon · 2022Article
- Immediate to short-term inflammatory response to biomaterial implanted in calvarium of mice.European journal of translational myology · 2022Article
- In Vivo Evaluation of 3D-Printed Silica-Based Bioactive Glass Scaffolds for Bone Regeneration.Journal of functional biomaterials · 2022Article
- Long-Term Effect of Honeycomb β-Tricalcium Phosphate on Zygomatic Bone Regeneration in Rats.Materials (Basel, Switzerland) · 2020Article
- Evaluation of the In Vivo Biological Effects of Marine Collagen and Hydroxyapatite Composite in a Tibial Bone Defect Model in Rats.Marine biotechnology (New York, N.Y.) · 2020Article
- Scaffolds and coatings for bone regeneration.Journal of materials science. Materials in medicine · 2020Review
- rhBMP2 alone does not induce macrophage polarization towards an increased inflammatory response.Molecular immunology · 2020Article
- Effect of Polymethylmethacrylate-Hydroxyapatite Composites on Callus Formation and Compressive Strength in Goat Vertebral Body.Malaysian orthopaedic journal · 2018Article
- Isolation and characterization of minipig perivascular stem cells for bone tissue engineering.Molecular medicine reports · 2018Article
- Bioactive Glasses: From Parent 45S5 Composition to Scaffold-Assisted Tissue-Healing Therapies.Journal of functional biomaterials · 2018Review
- 3D Printing and Electrospinning of Composite Hydrogels for Cartilage and Bone Tissue Engineering.Polymers · 2018Review
- Evaluation of BMMSCs-EPCs sheets for repairing alveolar bone defects in ovariectomized rats.Scientific reports · 2017Article
- [Treated dentin matrix enhances proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2016Article
- Evaluations of hydroxyapatite and bioactive glass in the repair of critical size bone defects in rat calvaria.Journal of oral biology and craniofacial researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches to the healing of damaged bone. Healing of large bone defects is achieved using implant materials that gradually integrate with the body after healing is completed. Such strategies require a multidisciplinary approach by material scientists, biological scientists, and clinicians. Development of materials for bone healing and exploration of the interactions thereof with the body are active research areas. In this review, we explore ongoing developments in the creation of materials for regenerating hard tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.