Evidence map›Paper›PMID 25995574›Full record

ArticleJournal of physical therapy science2015

Association between mean platelet volume and bone mineral density in patients with ankylosing spondylitis and diagnostic value of diffusion-weighted magnetic resonance imaging.

Hatice Resorlu, Mustafa Resorlu, Ferhat Gokmen, Ayla Akbal, Gurhan Adam, Erkam Komurcu, Ferdi Goksel, Mustafa Guven, Adem Bozkurt Aras, Abdullah Sariyildirim and 1 more

Abstract read
In one paragraph

Article in Journal of physical therapy science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mean platelet volume, red cell distribution width, platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios in patients with ankylosing spondylitis and their relationships with high-frequency hearing thresholds.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Trial
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hatice ResorluDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Mustafa ResorluDepartment of Radiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Ferhat GokmenDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Ayla AkbalDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Gurhan AdamDepartment of Radiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Erkam KomurcuDepartment of Orthopedics, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Ferdi GokselDepartment of Orthopedics, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Mustafa GuvenDepartment of Neurosurgery, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Adem Bozkurt ArasDepartment of Neurosurgery, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Abdullah SariyildirimDepartment of Radiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.
Sibel CevizciDepartment of Public Health, Faculty of Medicine, Canakkale Onsekiz Mart University, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[Purpose] The aim this study was to assess the relation between bone mineral density (BMD) and mean platelet volume (MPV) in ankylosing spondylitis (AS) patients, and evaluate the diagnostic role of the diffusion-weighted magnetic resonance imaging (MRI). [Subjects and Methods] Fifty patients diagnosed with AS were divided into two groups on the basis of BMD, a normal group (n=30) and an osteopenic (n=20) group. [Results] Duration of disease in the group with a normal BMD was 10.3±7.0 years, while it was 16.7±12.2 years in the osteopenia group. MPV was high in the osteopenia group, while no significant differences were observed between the groups in terms of apparent diffusion coefficient (ADC) and platelet distribution width (PDW). There was a positive correlation between MPV and duration of disease. Correlations between ADC value and the lumbar T score, femoral neck T score, and duration of disease were insignificant. A negative correlation was observed between BMD and disease duration. [Conclusion] Diffusion-weighted imaging provides valuable results in osteoporosis but is not a suitable technique for evaluating BMD in patients with AS because of the local and systemic inflammatory effects in the musculoskeletal system. The common pathophysiology of atherosclerosis and osteoporosis plays an important role in the negative correlation observed between MPV and BMD in patients with AS.

Indexed as

Ankylosing spondylitisBone mineral densityMean platelet volume

Identifiers

PMID25995574
PMCPMC4433995

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.