ArticlePlant physiology2015
MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
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99 citing papers in PubMed, 235 citations in OpenAlex.
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- Fine mapping and candidate gene analysis of a major QTL qHSW_11 for seed weight in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Exogenous Hormone Treatments Reveal Species-Specific Regulation of Individual Components of Root Architecture and Salt Ion Accumulation in Cultivated and Wild Tomatoes.Plant direct · 2026Article
- A soybean EIN transcription factor confers resistance to Phytophthora sojae and favorable agronomic traits.Plant cell reports · 2026Article
- Screening and Validation of Interacting Proteins of Receptor-like Cytoplasmic Kinase OsRLCK118 Involved in Rice Blast Resistance.Journal of fungi (Basel, Switzerland) · 2026Article
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- The miR172a-ERF416/413 module regulates soybean seed traits.Journal of integrative plant biology · 2025Article
- Physiological and Transcriptional Regulation of Salt Tolerance inPlants (Basel, Switzerland) · 2025Article
- Comparative Transcriptome and Hormonal Analysis Reveals the Mechanisms of Salt Tolerance in Rice.International journal of molecular sciences · 2025Article
- OsERF2 Acts as a Direct Downstream Target of OsEIL1 to Negatively Regulate Salt Tolerance in Rice.Rice (New York, N.Y.) · 2025Article
- Mechanosensing antagonizes ethylene signaling to promote root gravitropism in rice.Nature communications · 2025Article
- Beyond species and spatial boundaries: Enabling long-distance gene silencing in plants via guanidinium-siRNA nanoparticles.Plant biotechnology journal · 2025Article
- MHZ3: a key regulator of ethylene signaling in rice.aBIOTECH · 2025Review
- The Regulation of ROS and Phytohormones in Balancing Crop Yield and Salt Tolerance.Antioxidants (Basel, Switzerland) · 2025Review
- Ethylene Signaling in Plant Development and Stress Adaptation.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Identification of QTLs and a candidate gene affecting rice grain volume via high-density genetic mapping.Frontiers in plant science · 2025Article
- Multi-kernel feature extraction with dynamic fusion and downsampled residual feature embedding for predicting rice RNA N6-methyladenine sites.Briefings in bioinformatics · 2024Article
39 more citing papers are in PubMed but not listed here.
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10 authors at 1 institution in 1 country.
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Abstract
Ethylene plays important roles in plant growth, development, and stress responses. The ethylene signaling pathway has been studied extensively, mainly in Arabidopsis (Arabidopsis thaliana). However, the molecular mechanism of ethylene signaling is largely unknown in rice (Oryza sativa). Previously, we have isolated a set of rice ethylene-response mutants. Here, we characterized the mutant maohuzi6 (mhz6). Through map-based cloning, we found that MHZ6 encodes ETHYLENE INSENSITIVE3-LIKE1 (OsEIL1), a rice homolog of ETHYLENE INSENSITIVE3 (EIN3), which is the master transcriptional regulator of ethylene signaling in Arabidopsis. Disruption of MHZ6/OsEIL1 caused ethylene insensitivity mainly in roots, whereas silencing of the closely related OsEIL2 led to ethylene insensitivity mainly in coleoptiles of etiolated seedlings. This organ-specific functional divergence is different from the functional features of EIN3 and EIL1, both of which mediate the incomplete ethylene responses of Arabidopsis etiolated seedlings. In Arabidopsis, EIN3 and EIL1 play positive roles in plant salt tolerance. In rice, however, lack of MHZ6/OsEIL1 or OsEIL2 functions improves salt tolerance, whereas the overexpressing lines exhibit salt hypersensitivity at the seedling stage, indicating that MHZ6/OsEIL1 and OsEIL2 negatively regulate salt tolerance in rice. Furthermore, this negative regulation by MHZ6/OsEIL1 and OsEIL2 in salt tolerance is likely attributable in part to the direct regulation of HIGH-AFFINITY K(+) TRANSPORTER2;1 expression and Na(+) uptake in roots. Additionally, MHZ6/OsEIL1 overexpression promotes grain size and thousand-grain weight. Together, our study provides insights for the functional diversification of MHZ6/OsEIL1 and OsEIL2 in ethylene response and finds a novel mode of ethylene-regulated salt stress response that could be helpful for engineering salt-tolerant crops.
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