Evidence map›Paper›PMID 25995254›Full record

ArticleJournal of virology2015

Pseudorabies Virus Fast Axonal Transport Occurs by a pUS9-Independent Mechanism.

Gina R Daniel, Patricia J Sollars, Gary E Pickard, Gregory A Smith

Abstract read
In one paragraph

Article in Journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Frontiers in microbiology · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Assembly and Egress of an Alphaherpesvirus Clockwork.Advances in anatomy, embryology, and cell biology · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gina R DanielDepartment of Microbiology-Immunology, Northwestern University, Chicago, Illinois, USA.
Patricia J SollarsSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Gary E PickardSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Gregory A SmithDepartment of Microbiology-Immunology, Northwestern University, Chicago, Illinois, USA g-smith3@northwestern.edu.

Funding

CELLULAR &MOLECULAR BASIS OF DISEASE TRAINING PROGRAMT32GM008061 · NIGMS · NORTHWESTERN UNIVERSITY · PI CARTHEW, RICHARD W. · 1985 to 2022
$17.1M
Alpha-Herpesvirus Transport on AxonsR01AI056346 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SMITH, GREGORY ALLAN · 2004 to 2024
$6.8M
Homeostatic regulation of peripheral oscillators via autonomic circuitryR01NS077003 · NINDS · UNIVERSITY OF NEBRASKA LINCOLN · PI PICKARD, GARY EDWARD, SOLLARS, PATRICIA · 2012 to 2016
$1.8M
NIAID NIH HHS R01 AI056346NIGMS NIH HHS T32 GM008061NIGMS NIH HHS T32 GM08061NINDS NIH HHS R01 NS077003
6 · The paper itself

Abstract

Reactivation from latency results in transmission of neurotropic herpesviruses from the nervous system to body surfaces, referred to as anterograde axonal trafficking. The virus-encoded protein pUS9 promotes axonal dissemination by sorting virus particles into axons, but whether it is also an effector of fast axonal transport within axons is unknown. To determine the role of pUS9 in anterograde trafficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.

Indexed as

AnimalsAxonal TransportAxonsHerpesvirus 1, SuidIntracellular Signaling Peptides and ProteinsLipoproteinsPhosphoproteinsProtein TransportPseudorabiesSwineSwine DiseasesViral ProteinsIntracellular Signaling Peptides and ProteinsLipoproteinsPhosphoproteinsUS9 protein, Suid herpesvirus 1Viral Proteins

Identifiers

PMID25995254
PMCPMC4505671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.