ArticleGenetics2015
Worldwide Population Structure, Long-Term Demography, and Local Adaptation of Helicobacter pylori.
Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Review
- Antibiotic Resistance and Genetic Determinants ofInternational journal of molecular sciences · 2025Article
- Advances in Helicobacter pylori lipopolysaccharide structure and function.FEMS microbiology reviews · 2025Review
- Genomic insights into the antimicrobial resistance and virulence of Helicobacter pylori isolates from gastritis patients in Pereira, Colombia.BMC genomics · 2024Article
- Evidence for Admixture and Rapid Evolution During Glacial Climate Change in an Alpine Specialist.Molecular biology and evolution · 2024Article
- Comparative genomics of two Vietnamese Helicobacter pylori strains, CHC155 from a non-cardia gastric cancer patient and VN1291 from a duodenal ulcer patient.Scientific reports · 2023Article
- Pathogenomics of Helicobacter pylori.Current topics in microbiology and immunology · 2023Review
- The Role ofInternational journal of molecular sciences · 2022Review
- Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations.Nature communications · 2022Article
- Review
- Understanding the Genetic Diversity ofFrontiers in genetics · 2022Article
- Assessment of the diagnostic accuracy and relevance of a novel ELISA system developed for seroepidemiologic surveys of Helicobacter pylori infection in African settings.PLoS neglected tropical diseases · 2021Article
- Dispersal strategies shape persistence and evolution of human gut bacteria.Cell host & microbe · 2021Article
- Biases in Demographic Modeling Affect Our Understanding of Recent Divergence.Molecular biology and evolution · 2021Article
- Article
- Role of TNF-α-Inducing Protein Secreted byToxins · 2021Review
- Whole-Genome-BasedFrontiers in microbiology · 2021Article
- Article
- A novel taxon selection method, aimed at minimizing recombination, clarifies the discovery of a new sub-population ofEvolutionary applications · 2020Article
- Detecting Positive Selection in Populations Using Genetic Data.Methods in molecular biology (Clifton, N.J.) · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Helicobacter pylori is an important human pathogen associated with serious gastric diseases. Owing to its medical importance and close relationship with its human host, understanding genomic patterns of global and local adaptation in H. pylori may be of particular significance for both clinical and evolutionary studies. Here we present the first such whole genome analysis of 60 globally distributed strains, from which we inferred worldwide population structure and demographic history and shed light on interesting global and local events of positive selection, with particular emphasis on the evolution of San-associated lineages. Our results indicate a more ancient origin for the association of humans and H. pylori than previously thought. We identify several important perspectives for future clinical research on candidate selected regions that include both previously characterized genes (e.g., transcription elongation factor NusA and tumor necrosis factor alpha-inducing protein Tipα) and hitherto unknown functional genes.
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Registered trials
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