ReviewHead & neck2016
Getting personal: Head and neck cancer management in the era of genomic medicine.
Review in Head & neck, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Genetic and epigenetic landscape of early-onset oral squamous cell carcinoma: Insights of genomic underserved and underrepresented populations.Genetics and molecular biology · 2024Article
- What is the predictive value of OroGrams to estimate survival rates of HPV-positive oropharyngeal squamous cell carcinoma?Evidence-based dentistry · 2022Article
- Patient and Provider Perspectives Regarding Enrollment in Head and Neck Cancer Research.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2020Article
- Article
- The genomic landscape of UM-SCC oral cavity squamous cell carcinoma cell lines.Oral oncology · 2018Article
- Pathogenetic Analysis of Sinonasal Teratocarcinosarcomas Reveal Actionable β-catenin Overexpression and a β-catenin Mutation.Journal of neurological surgery. Part B, Skull base · 2017Article
- Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma.Oral oncology · 2017Article
- Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC.Journal of Cancer · 2017Review
- Genetic determinants in head and neck squamous cell carcinoma and their influence on global personalized medicine.Genes & cancer · 2016Article
- Moving towards personalised therapy in head and neck squamous cell carcinoma through analysis of next generation sequencing data.European journal of cancer (Oxford, England : 1990) · 2016Review
- A review of drugs in development for the personalized treatment of head and neck squamous cell carcinoma.Expert review of precision medicine and drug development · 2016Article
- Differential compensation mechanisms define resistance to PI3K inhibitors inOtorhinolaryngology-head and neck surgery · 2016Article
- The potential for tumor suppressor gene therapy in head and neck cancer.Discovery medicine · 2016Review
- The Tip of the Iceberg: Clinical Implications of Genomic Sequencing Projects in Head and Neck Cancer.Cancers · 2015Review
- Personalizing Medicine in Head and Neck Squamous Cell Carcinoma: The Rationale for Combination Therapies.Medical research archivesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundGenetic testing is rapidly becoming an important tool in the management of patients with head and neck cancer. As we enter the era of genomics and personalized medicine, providers should be aware of testing options, counseling resources, and the benefits, limitations, and future of personalized therapy.
methodsThis article offers a primer to assist clinicians treating patients in anticipating and managing the inherent practical and ethical challenges of cancer care in the genomic era.
resultsClinical applications of genomics for head and neck cancer are emerging. We discuss the indications for genetic testing, types of testing available, implications for care, privacy/disclosure concerns, and ethical considerations. Hereditary genetic syndromes associated with head and neck neoplasms are reviewed, and online genetics resources are provided.
conclusionThis article summarizes and contextualizes the evolving diagnostic and therapeutic options that impact the care of patients with head and neck cancer in the genomic era. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2250-E2258, 2016.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.