ArticleCerebral cortex (New York, N.Y. : 1991)2016
Individual Differences in Reward and Somatosensory-Motor Brain Regions Correlate with Adiposity in Adolescents.
Article in Cerebral cortex (New York, N.Y. : 1991), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03766191 (The Relation of Genetic Factors, Food Cues, and Self-Regulation With Excess Consumption and Adiposity in Children), which is not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Relation of Genetic Factors, Food Cues, and Self-Regulation With Excess Consumption and Adiposity in Children
Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Brain structural and functional changes in childhood and adolescent obesity: a systematic review of MRI studies.Frontiers in human neuroscience · 2026Pooled it
- The Effects of Food Advertisements on Food Intake and Neural Activity: A Systematic Review and Meta-Analysis of Recent Experimental Studies.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Brain responses to watching food commercials compared with nonfood commercials: a meta-analysis on neuroimaging studies.Public health nutrition · 2021Pooled it
- Oxytocin reduces the functional connectivity between brain regions involved in eating behavior in men with overweight and obesity.International journal of obesity (2005) · 2020Trial
- Television food advertisement exposure and FTO rs9939609 genotype in relation to excess consumption in children.International journal of obesity (2005) · 2017Trial
- Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study.Metabolism: clinical and experimental · 2016Trial
- Magnetoencephalography in human neuroscience research: planning, piloting, implementation and quality assurance.Nature protocols · 2026Review
- Attentional biases in self-control are associated with reward cue-related brain activity.Social cognitive and affective neuroscience · 2026Article
- Structural and Functional Brain Changes in Children and Adolescents With Obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Altered brain function and structure in youth-onset type 2 diabetes.European journal of endocrinology · 2025Article
- The Power of Food Advertisements: A Brief Mindfulness Instruction Does Not Prevent Psychophysiological Responses Triggered by Food Ads.Brain sciences · 2025Article
- Structural connectome manifold changes related to body mass index and their associations with eating psychopathology.NeuroImage. Clinical · 2025Article
- Exposure to gestational diabetes mellitus in utero impacts hippocampal functional connectivity in response to food cues in children.International journal of obesity (2005) · 2024Article
- FTO variant is associated with changes in BMI, ghrelin, and brain function following bariatric surgery.JCI insight · 2024Article
- Obesity is associated with alterations in anatomical connectivity of frontal-corpus callosum.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Effect of Preadolescents' Obesity on Inhibitory Control During Stop-Signal Task: A Functional EEG Network Study.IEEE open journal of engineering in medicine and biology · 2024Article
- Biobehavioral susceptibility for obesity in childhood: Behavioral, genetic and neuroimaging studies of appetite.Physiology & behavior · 2023Review
- Paediatric obesity and metabolic syndrome associations with cognition and the brain in youth: Current evidence and future directions.Pediatric obesity · 2023Review
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- The body mass index is associated with increased temporal variability of functional connectivity in brain reward system.Frontiers in nutrition · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The prevalence of adolescent obesity has increased dramatically over the past three decades, and research has documented that the number of television shows viewed during childhood is associated with greater risk for obesity. In particular, considerable evidence suggests that exposure to food marketing promotes eating habits that contribute to obesity. The present study examines neural responses to dynamic food commercials in overweight and healthy-weight adolescents using functional magnetic resonance imaging (fMRI). Compared with non-food commercials, food commercials more strongly engaged regions involved in attention and saliency detection (occipital lobe, precuneus, superior temporal gyri, and right insula) and in processing rewards [left and right nucleus accumbens (NAcc) and left orbitofrontal cortex (OFC)]. Activity in the left OFC and right insula further correlated with subjects' percent body fat at the time of the scan. Interestingly, this reward-related activity to food commercials was accompanied by the additional recruitment of mouth-specific somatosensory-motor cortices-a finding that suggests the intriguing possibility that higher-adiposity adolescents mentally simulate eating behaviors and offers a potential neural mechanism for the formation and reinforcement of unhealthy eating habits that may hamper an individual's ability lose weight later in life.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.