ArticleGenome biology and evolution2015
Genome-Wide Analysis in Three Fusarium Pathogens Identifies Rapidly Evolving Chromosomes and Genes Associated with Pathogenicity.
Article in Genome biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 102 citations in OpenAlex.
- An ABC-B Transporter Helps ProtectJournal of fungi (Basel, Switzerland) · 2026Article
- Divergent pathogenic strategies of Fusarium species in Panax notoginseng and biocontrol by a Bacillus-Serratia consortium.BMC plant biology · 2026Article
- From Morphology to Multi-Omics: A New Age of Fusarium Research.Pathogens (Basel, Switzerland) · 2025Review
- Gap-free comparative genomics uncover virulence factors for Fusarium wilt of watermelons.PLoS pathogens · 2025Article
- Repeat-induced point mutations driving Parastagonospora nodorum genomic diversity are balanced by selection against non-synonymous mutations.Communications biology · 2024Article
- Comparative genomics and transcriptomics reveal differences in effector complement and expression between races ofFrontiers in plant science · 2024Article
- A roadmap to understanding diversity and function of coral reef-associated fungi.FEMS microbiology reviews · 2022Article
- Transcriptome Analysis ofGenes · 2022Article
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- Defence response in plants and animals against a common fungal pathogenCurrent research in microbial sciences · 2022Review
- A single amino acid polymorphism in a conserved effector of the multihost blast fungus pathogen expands host-target binding spectrum.PLoS pathogens · 2021Article
- Genome-wide association study for deoxynivalenol production and aggressiveness in wheat and rye head blight by resequencing 92 isolates of Fusarium culmorum.BMC genomics · 2021Article
- Rapid sequence evolution driven by transposable elements at a virulence locus in a fungal wheat pathogen.BMC genomics · 2021Article
- Whole-Genome Comparisons of Ergot Fungi Reveals the Divergence and Evolution of Species within the Genus Claviceps Are the Result of Varying Mechanisms Driving Genome Evolution and Host Range Expansion.Genome biology and evolution · 2021Article
- Whole genome analysis of the koa wilt pathogen (Fusarium oxysporum f. sp. koae) and the development of molecular tools for early detection and monitoring.BMC genomics · 2020Article
- De novo sequencing, assembly and functional annotation of Armillaria borealis genome.BMC genomics · 2020Article
- Pathogenomics and Management ofPathogens (Basel, Switzerland) · 2020Review
- Three-Locus Sequence Identification and Differential Tebuconazole Sensitivity Suggest NovelPathogens (Basel, Switzerland) · 2020Article
- Pathogenicity and Virulence Factors ofMicroorganisms · 2020Review
- A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici.BMC biology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogens and hosts are in an ongoing arms race and genes involved in host-pathogen interactions are likely to undergo diversifying selection. Fusarium plant pathogens have evolved diverse infection strategies, but how they interact with their hosts in the biotrophic infection stage remains puzzling. To address this, we analyzed the genomes of three Fusarium plant pathogens for genes that are under diversifying selection. We found a two-speed genome structure both on the chromosome and gene group level. Diversifying selection acts strongly on the dispensable chromosomes in Fusarium oxysporum f. sp. lycopersici and on distinct core chromosome regions in Fusarium graminearum, all of which have associations with virulence. Members of two gene groups evolve rapidly, namely those that encode proteins with an N-terminal [SG]-P-C-[KR]-P sequence motif and proteins that are conserved predominantly in pathogens. Specifically, 29 F. graminearum genes are rapidly evolving, in planta induced and encode secreted proteins, strongly pointing toward effector function. In summary, diversifying selection in Fusarium is strongly reflected as genomic footprints and can be used to predict a small gene set likely to be involved in host-pathogen interactions for experimental verification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.