Evidence map›Paper›PMID 25994840›Full record

ArticleBMC bioinformatics2015

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams.

Henry Heberle, Gabriela Vaz Meirelles, Felipe R da Silva, Guilherme P Telles, Rosane Minghim

Abstract read
In one paragraph

Article in BMC bioinformatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,417 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,417citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,417 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Accelerated epigenetic age in hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Pooled it
  2. Global Microbiome: Core and Unique Signatures Across Diverse Populations.International journal of molecular sciences · 2026
    Pooled it
  3. Trial
  4. IL-1β/IL-6 inflammatory crosstalk drives DNA methylation and histone remodeling associated with cytokine induced senescence in luminal breast cancer.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
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1,357 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Henry HeberleUniversidade de São Paulo, Instituto de Ciências Matemáticas e de Computação, Av. Trabalhador São-carlense, 400, São Carlos SP, Brazil. henry@icmc.usp.br.
Gabriela Vaz MeirellesLaboratório Nacional de Biociências, Campinas SP, Caixa Postal 6192, Brazil. gabriela.meirelles@lnbio.cnpem.br.
Felipe R da SilvaEmbrapa Informática Agropecuária, Av. André Tosello, 209, Campinas SP, Brazil. felipe.silva@embrapa.br.
Guilherme P TellesUniversidade Estadual de Campinas, Instituto de Computação, Av. Albert Einstein, 1251, Campinas SP, Brazil. gpt@ic.unicamp.br.
Rosane MinghimUniversidade de São Paulo, Instituto de Ciências Matemáticas e de Computação, Av. Trabalhador São-carlense, 400, São Carlos SP, Brazil. rminghim@icmc.usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSet comparisons permeate a large number of data analysis workflows, in particular workflows in biological sciences. Venn diagrams are frequently employed for such analysis but current tools are limited.

resultsWe have developed InteractiVenn, a more flexible tool for interacting with Venn diagrams including up to six sets. It offers a clean interface for Venn diagram construction and enables analysis of set unions while preserving the shape of the diagram. Set unions are useful to reveal differences and similarities among sets and may be guided in our tool by a tree or by a list of set unions. The tool also allows obtaining subsets' elements, saving and loading sets for further analyses, and exporting the diagram in vector and image formats. InteractiVenn has been used to analyze two biological datasets, but it may serve set analysis in a broad range of domains.

conclusionsInteractiVenn allows set unions in Venn diagrams to be explored thoroughly, by consequence extending the ability to analyze combinations of sets with additional observations, yielded by novel interactions between joined sets. InteractiVenn is freely available online at: www.interactivenn.net .

Indexed as

Computer GraphicsData Interpretation, StatisticalInternetSoftwareBiomarkers, TumorComputational BiologyGenome, PlantHumansMaleMusaPlant ProteinsProstatic NeoplasmsProteomicsTumor Cells, CulturedBiomarkers, TumorPlant Proteins

Identifiers

PMID25994840
PMCPMC4455604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.