Evidence map›Paper›PMID 25994737›Full record

ArticleThe Journal of the Acoustical Society of America2015

Fine-resolution maps of acoustic properties at 250 MHz of unstained fixed murine retinal layers.

Daniel Rohrbach, Harriet O Lloyd, Ronald H Silverman, Jonathan Mamou

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Advanced Topics in Quantitative Acoustic Microscopy.Advances in experimental medicine and biology · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Analysis and Design of High-Frequency 1-D CMUT Imaging Arrays in Noncollapsed Mode.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daniel RohrbachLizzi Center for Biomedical Engineering, Riverside Research, New York, New York 10038, USA drohrbach@riversideresearch.org.
Harriet O LloydDepartment of Ophthalmology, Columbia University Medical Center, New York, New York 10032, USA hl2596@cumc.columbia.edu.
Ronald H SilvermanLizzi Center for Biomedical Engineering, Riverside Research, New York, New York 10038, USA rs3072@cumc.columbia.edu, JMamou@RiversideResearch.org.
Jonathan MamouLizzi Center for Biomedical Engineering, Riverside Research, New York, New York 10038, USA rs3072@cumc.columbia.edu, JMamou@RiversideResearch.org.
Riverside Research Institute · USColumbia University Irving Medical Center · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Ultrasound Scattering Models for Detection of Metastases in Axillary Lymph NodesR21EB016117 · NIBIB · RIVERSIDE RESEARCH INSTITUTE · PI MAMOU, JONATHAN · 2013 to 2014
$395k
NEI NIH HHS P30 EY019007NEI NIH HHS P30EY019007NIBIB NIH HHS R21 EB016117NIBIB NIH HHS R21EB016117
6 · The paper itself

Abstract

Ex vivo assessment of microscale tissue biomechanical properties of the mammalian retina could offer insights into diseases such as keratoconus, and macular degeneration. A 250-MHz scanning acoustic microscope (7-μm resolution) has been constructed to derive two-dimensional quantitative maps of attenuation (α), speed of sound (c), acoustic impedance (Z), bulk modulus (B), and mass density ( ρ). The two-dimensional maps were compared to coregistered hematoxylin-and-eosin stained sections. This study is the first to quantitatively assess  α, c, Z, B, and ρ of individual retinal layers of mammalian animals at high ultrasound frequencies. Significant differences in these parameters between the layers were demonstrated.

Indexed as

Microscopy, AcousticAlcohol OxidoreductasesAnimalsBiomechanical PhenomenaElastic ModulusGenotypeImage Processing, Computer-AssistedMice, KnockoutPhenotypeRetinaAlcohol Oxidoreductasesretinol dehydrogenase 5

Identifiers

PMID25994737
PMCPMC4425732
OpenAlexW1543536544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.