Evidence map›Paper›PMID 25994481›Full record

ArticleScientific reports2015

A new look at the essence of the imaging photoplethysmography.

Alexei A Kamshilin, Ervin Nippolainen, Igor S Sidorov, Petr V Vasilev, Nikolai P Erofeev, Natalia P Podolian, Roman V Romashko

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 3 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 3 syntheses or guidelines pooled it, 240 citations in OpenAlex.

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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Alexei A Kamshilin1] Department of Applied Physics, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland [2] Scientific-Technical Centre for Computational Optics, Photonics and Imaging, ITMO University, 197101 St. Petersburg, Russia.
Ervin NippolainenDepartment of Applied Physics, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.
Igor S SidorovDelfin Technologies Ltd., FI- 70210 Kuopio, Finland.
Petr V VasilevFaculty of Medicine, St. Petersburg State University, 199034 St. Petersburg, Russia.
Nikolai P ErofeevFaculty of Medicine, St. Petersburg State University, 199034 St. Petersburg, Russia.
Natalia P Podolian1] School of Natural Sciences, Far-Eastern Federal University, 690950 Vladivostok, Russia [2] Lab. of Precision Optical Measurement Techniques, Institute of Automation and Control Processes FEB RAS, 690041 Vladivostok, Russia.
Roman V Romashko1] School of Natural Sciences, Far-Eastern Federal University, 690950 Vladivostok, Russia [2] Lab. of Precision Optical Measurement Techniques, Institute of Automation and Control Processes FEB RAS, 690041 Vladivostok, Russia.
Far Eastern Federal University · RUSt Petersburg University · RUUniversity of Eastern Finland · FIDelfin Technologies (Finland) · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoplethysmography (PPG) is a noninvasive optical method accepted in the clinical use for measurements of arterial oxygen saturation. It is widely believed that the light intensity after interaction with the biological tissue in vivo is modulated at the heartbeat frequency mainly due to pulsatile variations of the light absorption caused by arterial blood-volume pulsations. Here we report experimental observations, which are not consistent with this model and demonstrate the importance of elastic deformations of the capillary bed in the formation of the PPG waveform. These results provide new insight on light interaction with live tissue. To explain the observations we propose a new model of PPG in which pulse oscillations of the arterial transmural pressure deform the connective-tissue components of the dermis resulting in periodical changes of both the light scattering and absorption. These local changes of the light-interaction parameters are detected as variations of the light intensity returned to a photosensitive camera. Therefore, arterial pulsations can be indirectly monitored even by using the light, which slightly penetrates into the biological tissue.

Indexed as

PhotoplethysmographySignal Processing, Computer-AssistedAdultAgedAged, 80 and overBlood PressureFemaleHandHumansMaleMiddle AgedOxygenPulse Wave AnalysisRegional Blood FlowVideo RecordingOxygen

Identifiers

PMID25994481
PMCPMC4440202
OpenAlexW328151516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.