SynthesisThe Cochrane database of systematic reviews2015
Alginate dressings for treating pressure ulcers.
Synthesis in The Cochrane database of systematic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Plant-derived alginate polysaccharide hydrogels in sport and exercise nutrition: implications for carbohydrate metabolism, gastrointestinal integrity, exercise recovery, and athletic performance.Frontiers in nutrition · 2026Pooled it
- Pooled it
- Rigid dressings versus soft dressings for transtibial amputations.The Cochrane database of systematic reviews · 2019Pooled it
- Support surfaces for treating pressure ulcers.The Cochrane database of systematic reviews · 2018Pooled it
- Dressings and topical agents for treating pressure ulcers.The Cochrane database of systematic reviews · 2017Pooled it
- Antibiotics and antiseptics for pressure ulcers.The Cochrane database of systematic reviews · 2016Pooled it
- Review
- Multifunctional Carbon-Based Nanocomposite Hydrogels for Wound Healing and Health Management.Gels (Basel, Switzerland) · 2025Review
- Advanced biomaterials in pressure ulcer prevention and care: from basic research to clinical practice.Frontiers in bioengineering and biotechnology · 2025Review
- Biomedical materials for wound dressing: recent advances and applications.RSC advances · 2023Review
- Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing.Membranes · 2022Review
- Recent progress in nanocomposites of carbon dioxide fixation derived reproducible biomedical polymers.Frontiers in chemistry · 2022Review
- An Overview of Cellulose Derivatives-Based Dressings for Wound-Healing Management.Pharmaceuticals (Basel, Switzerland) · 2021Review
- First-Line Interactive Wound Dressing Update: A Comprehensive Review of the Evidence.Frontiers in pharmacology · 2020Review
- A Randomized Control Trial Comparing Transparent Film Dressings and Conventional Occlusive Dressings for Elective Surgical Procedures.Open access Macedonian journal of medical sciences · 2019Article
- Silver in Wound Care-Friend or Foe?: A Comprehensive Review.Plastic and reconstructive surgery. Global open · 2019Article
- Article
- Interventions for pressure ulcers: a summary of evidence for prevention and treatment.Spinal cord · 2018Review
- Review of the Current Management of Pressure Ulcers.Advances in wound care · 2018Review
- Engineered Biopolymeric Scaffolds for Chronic Wound Healing.Frontiers in physiology · 2016Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundPressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers. This review is part of a suite of Cochrane reviews investigating the use of dressings in the treatment of pressure ulcers. Each review will focus on a particular dressing type.
objectivesTo assess the effects of alginate dressings for treating pressure ulcers in any care setting. SEARCH
methodsFor this review, in April 2015 we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication. SELECTION CRITERIA: Published or unpublished randomised controlled trials (RCTs) comparing the effects of alginate with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above). DATA COLLECTION AND ANALYSIS: Two review authors independently performed study selection, risk of bias assessment and data extraction. MAIN
resultsWe included six studies (336 participants) in this review; all studies had two arms. The included studies compared alginate dressings with six other interventions that included: hydrocolloid dressings, silver containing alginate dressings, and radiant heat therapy. Each of the six comparisons included just one study and these had limited participant numbers and short follow-up times. All the evidence was of low or very low quality. Where data were available there was no evidence of a difference between alginate dressings and alternative treatments in terms of complete wound healing or adverse events. AUTHORS'
conclusionsThe relative effects of alginate dressings compared with alternative treatments are unclear. The existing trials are small, of short duration and at risk of bias. Decision makers may wish to consider aspects such as cost of dressings and the wound management properties offered by each dressing type, for example, exudate management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.