Evidence map›Paper›PMID 25994366›Full record

SynthesisThe Cochrane database of systematic reviews2015

Alginate dressings for treating pressure ulcers.

Jo C Dumville, Samantha J Keogh, Zhenmi Liu, Nikki Stubbs, Rachel M Walker, Mathew Fortnam

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 6 pooled it
21.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Rigid dressings versus soft dressings for transtibial amputations.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Support surfaces for treating pressure ulcers.The Cochrane database of systematic reviews · 2018
    Pooled it
  5. Dressings and topical agents for treating pressure ulcers.The Cochrane database of systematic reviews · 2017
    Pooled it
  6. Antibiotics and antiseptics for pressure ulcers.The Cochrane database of systematic reviews · 2016
    Pooled it
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Silver in Wound Care-Friend or Foe?: A Comprehensive Review.Plastic and reconstructive surgery. Global open · 2019
    Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jo C DumvilleSchool of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK, M13 9PL.
Samantha J Keogh
Zhenmi Liu
Nikki Stubbs
Rachel M Walker
Mathew Fortnam
National Health and Medical Research Council · AUUniversity of Manchester · GBSt Mary's Hospital · GBUniversity of York · GB

Funding

Department of Health 13/89/08
6 · The paper itself

Abstract

backgroundPressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers. This review is part of a suite of Cochrane reviews investigating the use of dressings in the treatment of pressure ulcers. Each review will focus on a particular dressing type.

objectivesTo assess the effects of alginate dressings for treating pressure ulcers in any care setting. SEARCH

methodsFor this review, in April 2015 we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication. SELECTION CRITERIA: Published or unpublished randomised controlled trials (RCTs) comparing the effects of alginate with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above). DATA COLLECTION AND ANALYSIS: Two review authors independently performed study selection, risk of bias assessment and data extraction. MAIN

resultsWe included six studies (336 participants) in this review; all studies had two arms. The included studies compared alginate dressings with six other interventions that included: hydrocolloid dressings, silver containing alginate dressings, and radiant heat therapy. Each of the six comparisons included just one study and these had limited participant numbers and short follow-up times. All the evidence was of low or very low quality. Where data were available there was no evidence of a difference between alginate dressings and alternative treatments in terms of complete wound healing or adverse events. AUTHORS'

conclusionsThe relative effects of alginate dressings compared with alternative treatments are unclear. The existing trials are small, of short duration and at risk of bias. Decision makers may wish to consider aspects such as cost of dressings and the wound management properties offered by each dressing type, for example, exudate management.

Indexed as

BandagesAlginatesBandages, HydrocolloidDextransGlucuronic AcidHexuronic AcidsHumansHyperthermia, InducedPressure UlcerRandomized Controlled Trials as TopicSilver CompoundsSilver SulfadiazineSulfadiazineAlginatesdextranomerDextransGlucuronic AcidHexuronic AcidsSilver CompoundsSilver SulfadiazineSulfadiazine

Identifiers

PMID25994366
PMCPMC10555387
OpenAlexW2561720216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.