Evidence map›Paper›PMID 25994192›Full record

ArticleEuropean radiology2015

Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee.

Wouter Stomp, Monique Reijnierse, Margreet Kloppenburg, Renée de Mutsert, Judith V M G Bovée, Martin den Heijer, Johan L Bloem, NEO study group

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 68 citations in OpenAlex.

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  10. Prevalence and characteristics of benign cartilaginous tumours of the knee joint as identified on MRI scans.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  11. Article
  12. Benign incidental do-not-touch bone lesions.The British journal of radiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wouter StompDepartment of Radiology, C2-S, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. w.stomp@lumc.nl.
Monique ReijnierseDepartment of Radiology, C2-S, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Margreet KloppenburgDepartment of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
Renée de MutsertDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Judith V M G BovéeDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Martin den HeijerDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Johan L BloemDepartment of Radiology, C2-S, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
NEO study group
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose was to determine prevalence of enchondromas and atypical cartilaginous tumour/chondrosarcoma grade 1 (ACT/CS1) of the knee on MRI in a large cohort study, namely the Netherlands Epidemiology of Obesity (NEO) study.

methodsParticipants aged 45 to 65 years were prospectively included, oversampling overweight and obese persons. Within a subgroup of participants, MRI of the right knee was performed and screened for incidental cartilaginous tumours, as defined by their characteristic location and appearance.

resultsForty-nine cartilaginous tumours were observed in 44 out of 1285 participants (estimated population prevalence 2.8 %, 95 % CI 2.0-4.0 %). Mean largest tumour diameter was 12 mm (range 2-31 mm). Eight participants with a tumour larger than 20 mm or a tumour with aggressive features were referred to rule out low-grade chondrosarcoma. One was lost to follow-up, three had histologically proven ACT/CS1 and four had dynamic contrast MRI findings consistent with benign enchondroma.

conclusionsIncidental cartilaginous tumours were relatively common on knee MRI and may be regarded as a normal concurrent finding. However, more tumours than expected were ACT/CS1. Because further examination was performed only when suspicion of chondrosarcoma was high, the actual prevalence might be even higher. KEY POINTS: • Incidental cartilaginous tumours are relatively common on knee MRI. • Most incidental cartilaginous tumours are small and lack suspicious features. • Small cartilaginous tumours without suspicious findings may be a normal concurrent finding. • Large tumours and/or those with suspicious findings should be further investigated. • Atypical cartilaginous tumour/chondrosarcoma grade 1 was found more often than expected.

Indexed as

Incidental FindingsMagnetic Resonance ImagingAgedBone NeoplasmsCartilageChondromaChondrosarcomaCohort StudiesFemaleHumansKnee JointMaleMiddle AgedNetherlandsPrevalenceProspective StudiesChondromaChondrosarcomaIncidental findingsKneeMagnetic resonance imaging

Identifiers

PMID25994192
PMCPMC4636526
OpenAlexW259555097

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.