ArticleNature2015
Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Erratum issuedAbstract readLetter
In one paragraph
Article in Nature, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 80 papers.
0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed.
- Article
- Neural peer pressure: intercellular dynamics and emergent phenotypes in the mosaic Rett syndrome brain.Cell communication and signaling : CCS · 2026Review
- Toward an NGF-based therapy for Rett syndrome.Frontiers in neuroscience · 2026Review
- Myeloid lineage C3 induces reactive gliosis and neuronal stress during CNS inflammation.Nature communications · 2025Article
- Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity.Nature communications · 2025Article
- Neuronal Ceroid Lipofuscinosis-Concepts, Classification, and Avenues for Therapy.CNS neuroscience & therapeutics · 2025Review
- Enhancing cognitive-motor recovery in Rett syndrome: effects of integrated intervention on neuropsychological and motor outcome.Frontiers in psychology · 2025Article
- Review
- Rett syndrome.Nature reviews. Disease primers · 2024Review
- Human microglial cells as a therapeutic target in a neurodevelopmental disease model.Stem cell reports · 2024Article
- Allogenic microglia replacement: A novel therapeutic strategy for neurological disorders.Fundamental research · 2024Review
- Inhibition of MMP8 effectively alleviates manic-like behavior and reduces neuroinflammation by modulating astrocytic CEBPD.Journal of neuroinflammation · 2024Article
- Reversal of neurological deficits by painless nerve growth factor in a mouse model of Rett syndrome.Brain : a journal of neurology · 2024Article
- Donor bone marrow-derived macrophage engraftment into the central nervous system of patients following allogeneic transplantation.Blood advances · 2023Article
- Strategies for Manipulating Microglia to Determine Their Role in the Healthy and Diseased Brain.Neurochemical research · 2023Review
- Selective Xi reactivation and alternative methods to restore MECP2 function in Rett syndrome.Trends in genetics : TIG · 2022Review
- Murine models of clonal haematopoiesis to assess mechanisms of cardiovascular disease.Cardiovascular research · 2022Review
- Mechanisms underlying anxiety in Rett Syndrome: Translational insights from preclinical findings.Neuroscience applied · 2022Review
- Rett Syndrome andNeuropsychiatric disease and treatment · 2022Review
- Evolving Models and Tools for Microglial Studies in the Central Nervous System.Neuroscience bulletin · 2021Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issuedCorrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.2015 · Vigneau, Sebastian [Corrected to Vingeau, Sébastien]
Authors and funding
41 authors.
Jieqi WangDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Jan Eike WegenerDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
Teng-Wei Huang1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
Smitha SripathyClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Hector De Jesus-Cortes1] Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
Pin XuGraduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Stephanie TranDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Whitney KnobbeDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Vid LekoClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Jeremiah BrittDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
Ruth StarwaltDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Latisha McDanielDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
Chris S WardJan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
Diana ParraJan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
Benjamin NewcombClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Uyen LaoClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Cynthia NourigatClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
David A FlowersClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Sean CullenProgram in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
Nikolas L JorstadDepartment of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Yue YangDepartment of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Lena GlaskovaDepartment of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Sébastien Vingeau
Sebastian VigneauDepartment of Cell &Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Julia KozlitinaDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Michael J YetmanDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
Joanna L JankowskyDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
Sybille D ReichardtInstitute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
Holger M ReichardtInstitute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
Jutta GärtnerDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
Marisa S BartolomeiDepartment of Cell &Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Min Fang1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Keith Loeb1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
C Dirk KeeneDepartment of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Irwin BernsteinClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Margaret Goodell1] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [2] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [3] Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA [4] Stem Cell and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, USA [5] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA [6] Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
Daniel J BratDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Peter HuppkeDepartment of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
Jeffrey L Neul1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [3] Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA [4] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [5] Stem Cell and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, USA [6] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
Antonio Bedalov1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98105, USA.
Andrew A Pieper1] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [2] Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [3] Veterans Affairs, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [4] Weill Cornell Autism Research Program, Weill Cornell Medical College, New York, New York 10065, USA.
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9MWinship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5MPulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5MUNDERSTANDING FXTAS AMONG MALES WITH THE FMR1 PREMUTATIONP30HD024064 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI TOLIAS, KIMBERLY R · 1988 to 2013
$29.4MSYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2MVirology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BUTEL, JANET S · 1994 to 2015
$21.7MExpansion of Cardiac and Hematopoietic Pregenitors by Wnt and NotchU01HL100395 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BERNSTEIN, IRWIN D, MOON, RANDALL TODD · 2009 to 2015
$8.4MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8MTraining In Cell and Gene TherapyT32HL092332 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MALCOLM K. BRENNER, Bruno Di Stefano · 2008 to 2026
$6.9MWhite Matter Damage in Age-Related Cognitive DeclineR01AG031892 · NIA · UNIVERSITY OF WASHINGTON · PI MONTINE, THOMAS J · 2009 to 2016
$6.1MMouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SAHIN, MUSTAFA · 2016 to 2020
$5.2MMutidisciplinary Training;Brain Disorders &DevelopmentT32NS043124 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI SWANN, JOHN WILLIAM · 2002 to 2021
$4.6MNCI NIH HHS P30 CA125123NCI NIH HHS P30 CA138292NCRR NIH HHS S10 RR024574NHLBI NIH HHS T32 HL092332NHLBI NIH HHS U01 HL100395NIAID NIH HHS P30 AI036211NIA NIH HHS R01 AG031892NIA NIH HHS T32 AG000183NICHD NIH HHS P30 HD018655NICHD NIH HHS P30 HD024064NICHD NIH HHS R01 HD062553NICHD NIH HHS U54 HD083092NICHD NIH HHS U54 HD090255NIEHS NIH HHS P30 ES005605NINDS NIH HHS T32 NS043124
Abstract
PubMed holds no abstract for this paper.
Indexed as
Disease ProgressionAnimalsFemaleMaleMethyl-CpG-Binding Protein 2MicrogliaRett SyndromeMethyl-CpG-Binding Protein 2
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