Evidence map›Paper›PMID 25993486›Full record

ArticleArquivos brasileiros de cardiologia2015

Left Atrial Function in Patients with Chronic Chagasic Cardiomyopathy.

Claudia da Silva Fragata, Afonso Y Matsumoto, Felix J A Ramires, Fabio Fernandes, Paula de Cássia Buck, Vera Maria C Salemi, Luciano Nastari, Charles Mady, Barbara Maria Ianni

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Claudia da Silva FragataSeção Médica de Eletrofisiologia, Instituto Dante Pazzanese de Cardiologia, São Paulo, BR.
Afonso Y MatsumotoInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Felix J A RamiresInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Fabio FernandesInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Paula de Cássia BuckInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Vera Maria C SalemiInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Luciano NastariInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Charles MadyInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Barbara Maria IanniInstituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, BR.
Universidade de São Paulo · BRInstituto Dante Pazzanese de Cardiologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChagas disease is a cause of dilated cardiomyopathy, and information about left atrial (LA) function in this disease still lacks.

objectiveTo assess the different LA functions (reservoir, conduit and pump functions) and their correlation with the echocardiographic parameters of left ventricular (LV) systolic and diastolic functions.

methods10 control subjects (CG), and patients with Chagas disease as follows: 26 with the indeterminate form (GI); 30 with ECG alterations (GII); and 19 with LV dysfunction (GIII). All patients underwent M-mode and two-dimensional echocardiography, pulsed-wave Doppler and tissue Doppler imaging.

resultsReservoir function (Total Emptying Fraction: TEF): (p <0.0001), lower in GIII as compared to CG (p = 0.003), GI (p <0.001) and GII (p <0.001). Conduit function (Passive Emptying Fraction: PEF): (p = 0.004), lower in GIII (GIII and CG, p = 0.06; GI and GII, p = 0.06; and GII and GIII, p = 0.07). Pump function (Active Emptying Fraction: AEF): (p = 0.0001), lower in GIII as compared to CG (p = 0.05), GI (p<0.0001) and GII (p = 0.002). There was a negative correlation of E/e' (average) with the reservoir and pump functions (TEF and AEF), and a positive correlation of e' (average) with s' wave (both septal and lateral walls) and the reservoir, conduit and pump LA functions.

conclusionAn impairment of LA functions in Chagas cardiomyopathy was observed.

Indexed as

AdultAtrial Function, LeftCardiomyopathy, DilatedCase-Control StudiesChagas CardiomyopathyEchocardiography, DopplerFemaleHumansMaleMiddle AgedMyocardial ContractionReference ValuesStatistics, NonparametricStroke VolumeVentricular Dysfunction, Left

Identifiers

PMID25993486
PMCPMC4523285
OpenAlexW2124539399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.