Evidence map›Paper›PMID 25993417›Full record

ReviewMolecules (Basel, Switzerland)2015

Silver nanoparticles as potential antibacterial agents.

Gianluigi Franci, Annarita Falanga, Stefania Galdiero, Luciana Palomba, Mahendra Rai, Giancarlo Morelli, Massimiliano Galdiero

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 469 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
469citing papers in PubMed, 1 pooled it
53.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

469 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,623 citations in OpenAlex.

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  18. NanoformulatedNanomaterials (Basel, Switzerland) · 2026
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409 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Gianluigi FranciDipartimento di Biochimica, Biofisica e Patologia Generale, Seconda Università degli Studi di Napoli, Vico L. De Crecchio 7, 80138 Napoli, Italy. gianluigi.franci@unina2.it.
Annarita FalangaDepartment of Pharmacy, University of Naples Federico II, 80100 Naples, Italy. annarita.falanga@unina.it.
Stefania GaldieroDepartment of Pharmacy, University of Naples Federico II, 80100 Naples, Italy. stefania.galdiero@unina.it.
Luciana PalombaDepartment of Experimental Medicine, II University of Naples, 80138 Naples, Italy. luciana.palomba@igb.cnr.it.
Mahendra RaiDepartment of Biotechnology, Sant Gadge Baba Amravati University, Amravati, Maharashtra 444602, India. mkrai123@rediffmail.com.
Giancarlo MorelliDepartment of Pharmacy, University of Naples Federico II, 80100 Naples, Italy. giancarlo.morelli@unina.it.
Massimiliano GaldieroCIRPEB, and DFM, University of Naples Federico II, 80100 Naples, Italy. massimiliano.galdiero@unina2.it.
Institute of Biostructure and Bioimaging · ITUniversity of Naples Federico II · ITCentro Interuniversitario di Ricerca sui Peptidi Bioattivi · ITSant Gadge Baba Amravati University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-drug resistance is a growing problem in the treatment of infectious diseases and the widespread use of broad-spectrum antibiotics has produced antibiotic resistance for many human bacterial pathogens. Advances in nanotechnology have opened new horizons in nanomedicine, allowing the synthesis of nanoparticles that can be assembled into complex architectures. Novel studies and technologies are devoted to understanding the mechanisms of disease for the design of new drugs, but unfortunately infectious diseases continue to be a major health burden worldwide. Since ancient times, silver was known for its anti-bacterial effects and for centuries it has been used for prevention and control of disparate infections. Currently nanotechnology and nanomaterials are fully integrated in common applications and objects that we use every day. In addition, the silver nanoparticles are attracting much interest because of their potent antibacterial activity. Many studies have also shown an important activity of silver nanoparticles against bacterial biofilms. This review aims to summarize the emerging efforts to address current challenges and solutions in the treatment of infectious diseases, particularly the use of nanosilver antimicrobials.

Indexed as

Anti-Infective AgentsBiofilmsCommunicable DiseasesDrug Resistance, Multiple, BacterialHumansMetal NanoparticlesNanomedicineSilverAnti-Infective AgentsSilverAgNPsantibacterialbiofilmresistence

Identifiers

PMID25993417
PMCPMC6272636
OpenAlexW1559815414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.