SynthesisPloS one2015
Alcohol-related risk of suicidal ideation, suicide attempt, and completed suicide: a meta-analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 188 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
188 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- The Role of Social Support in Preventing Suicidal Ideations and Behaviors: A Systematic Review and Meta-Analysis.Journal of research in health sciences · 2024Pooled it
- Sex-Specific Association of Alcohol Use Disorder With Suicide Mortality: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Relationship of religion with suicidal ideation, suicide plan, suicide attempt, and suicide death: a meta-analysis.Journal of research in health sciences · 2022Pooled it
- Estimating the risk of suicide associated with mental disorders: A systematic review and meta-regression analysis.Journal of psychiatric research · 2021Pooled it
- Prevalence of Suicidality in Major Depressive Disorder: A Systematic Review and Meta-Analysis of Comparative Studies.Frontiers in psychiatry · 2021Pooled it
- Pooled it
- Risk factors for suicidal ideation and suicide attempt among medical students: A meta-analysis.PloS one · 2021Pooled it
- Determinants of Suicidality in the European General Population: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Metaanalysis of Mood and Substance Use Disorders in Proximal Risk for Suicide Deaths.Suicide & life-threatening behavior · 2019Pooled it
- Substance use and suicidal ideation and behaviour in low- and middle-income countries: a systematic review.BMC public health · 2018Pooled it
- The relationship between different dimensions of alcohol use and the burden of disease-an update.Addiction (Abingdon, England) · 2017Pooled it
- A meta-analysis of acute use of alcohol and the risk of suicide attempt.Psychological medicine · 2017Pooled it
- Smoking and Suicide: A Meta-Analysis.PloS one · 2016Pooled it
- Effectiveness of Integrating Suicide Care in Primary Care : Secondary Analysis of a Stepped-Wedge, Cluster Randomized Implementation Trial.Annals of internal medicine · 2024Trial
- Gender and addiction and other mental disorders comorbidity: sociodemographic, clinical, and treatment differences.Archives of women's mental health · 2023Trial
- Suicidal ideation and suicide attempts among high-school students reporting substance use in Northwest Ethiopia: a multischool cross-sectional study.Addictive behaviors reports · 2026Article
- Risk factors for repeat self-harm hospitalisation following hospital admissions for suicidal ideation and self-harm among Aboriginal and non-Aboriginal people: a retrospective cohort study using linked administrative data.Social psychiatry and psychiatric epidemiology · 2026Article
- Changes in Mental Health Networks Among High-Risk Suicide Groups in Korea Before and After the COVID-19 Pandemic.Journal of Korean medical science · 2026Article
- Elucidating psychosocial outcome profiles as a function of aggregate genetic risk for suicide attempt and alcohol use disorder.Translational psychiatry · 2026Article
- Examining the chronicity of suicidal thoughts and behaviors among Australian males.Social psychiatry and psychiatric epidemiology · 2026Article
128 more citing papers are in PubMed but not listed here.
Corrections and comments
- Expression of concern · 2022-12-19Concerns/Issues about Results and/or Conclusions ·
- Erratum issued
- Expression of concern
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral original studies have investigated the effect of alcohol use disorder (AUD) on suicidal thought and behavior, but there are serious discrepancies across the studies. Thus, a systematic assessment of the association between AUD and suicide is required.
methodsWe searched PubMed, Web of Science, and Scopus until February 2015. We also searched the Psycinfo web site and journals and contacted authors. We included observational (cohort, case-control, and cross-sectional) studies addressing the association between AUD and suicide. The exposure of interest was AUD. The primary outcomes were suicidal ideation, suicide attempt, and completed suicide. We assessed heterogeneity using Q-test and I2 statistic. We explored publication bias using the Egger's and Begg's tests and funnel plot. We meta-analyzed the data with the random-effects models. For each outcome we calculated the overall odds ratio (OR) or risk ratio (RR) with 95% confidence intervals (CI).
resultsWe included 31 out of 8548 retrieved studies, with 420,732 participants. There was a significant association between AUD and suicidal ideation (OR=1.86; 95% CI: 1.38, 2.35), suicide attempt (OR=3.13; 95% CI: 2.45, 3.81); and completed suicide (OR=2.59; 95% CI: 1.95, 3.23 and RR=1.74; 95% CI: 1.26, 2.21). There was a significant heterogeneity among the studies, but little concern to the presence of publication bias.
conclusionsThere is sufficient evidence that AUD significantly increases the risk of suicidal ideation, suicide attempt, and completed suicide. Therefore, AUD can be considered an important predictor of suicide and a great source of premature death.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.