ArticleScientific reports2015
The alternate role of direct and environmental transmission in fungal infectious disease in wildlife: threats for biodiversity conservation.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associated disease risk from the introduced generalist pathogen Sphaerothecum destruens: management and policy implications.Parasitology · 2016Pooled it
- Molecular characterization and virulence of fungal pathogens associated with mass mortalities in hilsa Shad (Tenualosa ilisha).Scientific reports · 2025Article
- Antifungal Drug Resistance.Current topics in microbiology and immunology · 2025Review
- Invasibility of a North American soil ecosystem to amphibian-killing fungal pathogens.Proceedings. Biological sciences · 2024Article
- Environmental associations of Ophidiomyces ophidiicola, the causative agent of ophidiomycosis in snakes.PloS one · 2024Article
- Emergence of the Fungal Rosette Agent in the World: Current Risk to Fish Biodiversity and Aquaculture.Journal of fungi (Basel, Switzerland) · 2023Review
- Soil Reservoir Dynamics ofJournal of fungi (Basel, Switzerland) · 2021Article
- Native drivers of fish life history traits are lost during the invasion process.Ecology and evolution · 2020Article
- The complete mitochondrial genome of a parasite at the animal-fungal boundary.Parasites & vectors · 2020Article
- The consequences of reservoir host eradication on disease epidemiology in animal communities.Emerging microbes & infections · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging fungal pathogens have substantial consequences for infected hosts, as revealed by the global decline of amphibian species from the chytrid fungus. According to the "curse of the Pharaoh" hypothesis, free-living infectious stages typical of fungal pathogens lengthen the timespan of transmission. Free-living infectious stages whose lifespan exceeds the infection time of their hosts are not constrained by virulence, enabling them to persist at high levels and continue transmitting to further sensitive hosts. Using the only Mesomycetozoea fungal species that can be cultured, Sphaerothecum destruens, we obtained tractable data on infectivity and pathogen life cycle for the first time. Here, based on the outcomes of a set of infectious trials and combined with an epidemiological model, we show a high level of dependence on direct transmission in crowded, confined environments and establish that incubation rate and length of infection dictate the epidemic dynamics of fungal disease. The spread of Mesomycetozoea in the wild raise ecological concerns for a range of susceptible species including birds, amphibians and mammals. Our results shed light on the risks associated with farming conditions and highlight the additional risk posed by invasive species that are highly abundant and can act as infectious reservoir hosts.
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