Evidence map›Paper›PMID 25992835›Full record

ArticleEmerging infectious diseases2015

Consensus on the development of vaccines against naturally acquired melioidosis.

Direk Limmathurotsakul, Simon G P Funnell, Alfredo G Torres, Lisa A Morici, Paul J Brett, Susanna Dunachie, Timothy Atkins, Daniel M Altmann, Gregory Bancroft, Sharon J Peacock and 1 more

Abstract readConsensus Statement
In one paragraph

Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. LVS ΔmBio · 2024
    Article
  7. Article
  8. Glanders (IDCases · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Recent Progress inPathogens (Basel, Switzerland) · 2021
    Review
  15. Article
  16. BipD ofMicroorganisms · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Human Melioidosis.Clinical microbiology reviews · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Direk Limmathurotsakul
Simon G P Funnell
Alfredo G Torres
Lisa A Morici
Paul J Brett
Susanna Dunachie
Timothy Atkins
Daniel M Altmann
Gregory Bancroft
Sharon J Peacock
Steering Group on Melioidosis Vaccine Development

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several candidates for a vaccine against Burkholderia pseudomallei, the causal bacterium of melioidosis, have been developed, and a rational approach is now needed to select and advance candidates for testing in relevant nonhuman primate models and in human clinical trials. Development of such a vaccine was the topic of a meeting in the United Kingdom in March 2014 attended by international candidate vaccine developers, researchers, and government health officials. The focus of the meeting was advancement of vaccines for prevention of natural infection, rather than for protection from the organism's known potential for use as a biological weapon. A direct comparison of candidate vaccines in well-characterized mouse models was proposed. Knowledge gaps requiring further research were identified. Recommendations were made to accelerate the development of an effective vaccine against melioidosis.

Indexed as

AnimalsBacterial VaccinesBurkholderia pseudomalleiCapital FinancingDisease Models, AnimalHumansMelioidosisMiceBacterial Vaccinesaerosol inhalationantimicrobial drugsbacteriaBurkholderia pseudomalleichallenge doseintranasalintraperitonealintravenousmelioidosispreventionSteering Group on Melioidosis Vaccine DevelopmentvaccineWhitmore’s disease

Identifiers

PMID25992835
PMCPMC4451926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.