Evidence map›Paper›PMID 25991820›Full record

ReviewClinical cancer research : an official journal of the American Association for Cancer Research2015

Emerging Treatment Paradigms in Radiation Oncology.

Quynh-Thu Le, Hiroki Shirato, Amato J Giaccia, Albert C Koong

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical cancer research : an official journal of the American Association for Cancer Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  12. Phase I study of theJournal for immunotherapy of cancer · 2020
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  17. Biological effects of radiation on cancer cells.Military Medical Research · 2018
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Quynh-Thu LeDepartment of Radiation Oncology, Stanford University, Stanford, California. qle@stanford.edu.
Hiroki ShiratoGlobal Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan.
Amato J GiacciaDepartment of Radiation Oncology, Stanford University, Stanford, California.
Albert C KoongDepartment of Radiation Oncology, Stanford University, Stanford, California.
Stanford Medicine · USSapporo Medical University · JP

Funding

TUMOR HYPOXIA--MOLECULAR STUDIES &CLINICAL EXPLOITATIONP01CA067166 · NCI · STANFORD UNIVERSITY · PI LE, QUYNH-THU XUAN · 1996 to 2017
$25.5M
Characterization and Targeting the GDNF and Other Pathways in Salivary Stem CellsR01DE025227 · NIDCR · STANFORD UNIVERSITY · PI LE, QUYNH-THU XUAN, XIAO, NAN · 2015 to 2019
$2.0M
Targeting Galectin-1 with radiation in lung cancerR01CA161585 · NCI · STANFORD UNIVERSITY · PI KOONG, ALBERT, LE, QUYNH-THU XUAN · 2012 to 2016
$1.6M
NCI NIH HHS P01 CA067166NCI NIH HHS P01CA067166NCI NIH HHS R01 CA161585NCI NIH HHS R01CA161585NIDCR NIH HHS R01 DE025227
6 · The paper itself

Abstract

Rapid advancements in radiotherapy and molecularly targeted therapies have resulted in the development of potential paradigm-shifting use of radiotherapy in the treatment of cancer. In this review, we discuss some of the most promising therapeutic approaches in the field of radiation oncology. These strategies include the use of highly targeted stereotactic radiotherapy and particle therapy as well as combining radiotherapy with agents that modulate the DNA damage response, augment the immune response, or protect normal tissues.

Indexed as

Molecular Targeted TherapyDNA DamageHumansImmunity, InnateNeoplasmsRadiation OncologyRadiosurgery

Identifiers

PMID25991820
PMCPMC4526434
OpenAlexW1864059051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.