Evidence map›Paper›PMID 25991803›Full record

ArticleCirculation. Heart failure2015

Updating the physiology and pathophysiology of cardiac Myosin-binding protein-C.

Martin M LeWinter, Bradley M Palmer

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Circulation. Heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Cardiac myosin binding protein-C SerScience advances · 2017
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Martin M LeWinterFrom the Cardiology Unit and the Department of Molecular Physiology and Biophysics, University of Vermont College of Medicine, Burlington. martin.lewinter@UVMHealth.org.
Bradley M PalmerFrom the Cardiology Unit and the Department of Molecular Physiology and Biophysics, University of Vermont College of Medicine, Burlington.

Funding

Ventricular and Cardiac Fiber Characterization and Integration CoreP01HL059408 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI ROBBINS, JEFFREY · 1999 to 2014
$26.4M
Advanced Glycation End-Products in Human MyocardiumR01HL089944 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LEWINTER, MARTIN M · 2008 to 2011
$2.6M
Myofilament-based mechanisms of diastolic dysfunction in HFpEFR01HL118524 · NHLBI · UNIVERSITY OF ARIZONA · PI GRANZIER, HENK L., LEWINTER, MARTIN M · 2014 to 2017
$2.5M
NHLBI NIH HHS P01 HL59408NHLBI NIH HHS R01HL089944
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiac Pacing, ArtificialVentricular Function, LeftAdrenergic beta-1 Receptor AgonistsAnimalsCardiotonic AgentsCarrier ProteinsHeart FailureMyocardial ContractionPapillary MusclesVentricular Dysfunction, LeftAdrenergic beta-1 Receptor AgonistsCardiotonic AgentsCarrier ProteinsEditorialsventricular function

Identifiers

PMID25991803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.