Evidence map›Paper›PMID 25991550›Full record

ArticleInflammopharmacology2015

Evaluation of the protective effect of Pterocarpus marsupium on acetic acid-induced ulcerative colitis in rats.

Merin Maria Mathew, Nguyen Vinh Han, A Murugesan, E Arun Raj, K G Prasanth

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  3. Article
  4. The Healing Effects of Hydroalcoholic Extract ofIranian journal of medical sciences · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Merin Maria MathewDepartment of Pharmacology, PSG College of Pharmacy, PO BOX NO 1674, Peelamedu, Coimbatore, 641004, Tamilnadu, India.
Nguyen Vinh Han
A Murugesan
E Arun Raj
K G Prasanth
PSG INSTITUTE OF TECHNOLOGY AND APPLIED RESEARCH · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to evaluate the effect of Pterocarpus marsupium (PM) on acetic acid (AA)-induced ulcerative colitis (UC) in rats. The rats were divided into five groups, each having six rats. PM extract 100 mg and 200 mg/kg was given orally to groups four and five, respectively, and standard drug sulfasalazine (100 mg/kg, p.o) to group three. Group two served as UC control animals, and group one control animals received vehicle for 7 days. UC was induced by administering AA (3 % v/v of 2 ml) to all the animals except group one. After 72 h, the animals were killed and the colon was dissected out for microscopic, clinical evaluation, histopathological study and biochemical estimation. PM (100 and 200 mg/kg)-treated group had significantly reduced colon inflammation and mucosal damage. The treatment also normalized the altered antioxidant enzyme levels (LPO, SOD and GSH). Histopathological studies support the effect. The protective effect of PM may be due to antiinflammatory and antioxidant properties.

Indexed as

Acetic AcidAnimalsAnti-Inflammatory AgentsAntioxidantsColitis, UlcerativeDisease Models, AnimalDose-Response Relationship, DrugFemalePlant ExtractsPterocarpusRatsRats, WistarSulfasalazineAcetic AcidAnti-Inflammatory AgentsAntioxidantsPlant ExtractsSulfasalazine

Identifiers

PMID25991550
OpenAlexW2106022355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.