ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2015
Statistical modeling to characterize relationships between knee anatomy and kinematics.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Pooled it
- Dependence of Muscle Moment Arms on In Vivo Three-Dimensional Kinematics of the Knee.Annals of biomedical engineering · 2017Trial
- Bone morphology and alignment features are associated with knee kinematics in healthy individuals: A scoping review.Journal of experimental orthopaedics · 2026Review
- Assessing the correlation between vastus medialis obliquus cross-sectional area and patellofemoral instability: a comparative magnetic resonance imaging study.Archives of orthopaedic and trauma surgery · 2025Article
- Increased kinematic changes in ascending compared with descending biplanar cut in open wedge high tibial osteotomy-a multibody simulation.Knee surgery & related research · 2024Article
- Exploiting Structural Consistency of Chest Anatomy for Unsupervised Anomaly Detection in Radiography Images.IEEE transactions on pattern analysis and machine intelligence · 2024Article
- Human foot form and function: variable and versatile, yet sufficiently related to predict function from form.Proceedings. Biological sciences · 2024Article
- Statistical shape modeling of the geometric morphology of the canine femur, tibia, and patella.Frontiers in veterinary science · 2024Article
- Instantaneous Generation of Subject-Specific Finite Element Models of the Hip Capsule.Bioengineering (Basel, Switzerland) · 2023Article
- Influence of Bone Morphology on In Vivo Tibio-Femoral Kinematics in Healthy Knees during Gait Activities.Journal of clinical medicine · 2022Article
- Automated Knee MR Images Segmentation of Anterior Cruciate Ligament Tears.Sensors (Basel, Switzerland) · 2022Article
- Statistical-Shape Prediction of Lower Limb Kinematics During Cycling, Squatting, Lunging, and Stepping-Are Bone Geometry Predictors Helpful?Frontiers in bioengineering and biotechnology · 2021Article
- Anterior Cruciate Ligament Graft Tunnel Placement and Graft Angle Are Primary Determinants of Internal Knee Mechanics After Reconstructive Surgery.The American journal of sports medicine · 2020Article
- Combined Estimation of Shape and Pose for Statistical Analysis of Articulating Joints.Shape in Medical Imaging : International Workshop, ShapeMI 2020, Held in Conjunction with MICCAI 2020, Lima, Peru, October 4, 2020, Proceedings · 2020Article
- Predicting Knee Joint Instability Using a Tibio-Femoral Statistical Shape Model.Frontiers in bioengineering and biotechnology · 2020Article
- The effect of articular geometry features identified using statistical shape modelling on knee biomechanics.Medical engineering & physics · 2019Article
- Statistical shape modeling of femur shape variability in female patients with hip dysplasia.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- A lower extremity model for muscle-driven simulation of activity using explicit finite element modeling.Journal of biomechanics · 2019Article
- A computationally efficient strategy to estimate muscle forces in a finite element musculoskeletal model of the lower limb.Journal of biomechanics · 2019Article
- Does Alignment in Statistical Shape Modeling of Left Atrium Appendage Impact Stroke Prediction?Computing in cardiology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The mechanics of the knee are complex and dependent on the shape of the articular surfaces and their relative alignment. Insight into how anatomy relates to kinematics can establish biomechanical norms, support the diagnosis and treatment of various pathologies (e.g., patellar maltracking) and inform implant design. Prior studies have used correlations to identify anatomical measures related to specific motions. The objective of this study was to describe relationships between knee anatomy and tibiofemoral (TF) and patellofemoral (PF) kinematics using a statistical shape and function modeling approach. A principal component (PC) analysis was performed on a 20-specimen dataset consisting of shape of the bone and cartilage for the femur, tibia and patella derived from imaging and six-degree-of-freedom TF and PF kinematics from cadaveric testing during a simulated squat. The PC modes characterized links between anatomy and kinematics; the first mode captured scaling and shape changes in the condylar radii and their influence on TF anterior-posterior translation, internal-external rotation, and the location of the femoral lowest point. Subsequent modes described relations in patella shape and alta/baja alignment impacting PF kinematics. The complex interactions described with the data-driven statistical approach provide insight into knee mechanics that is useful clinically and in implant design.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.