Observational studyBMJ open2015
Workload and management of childhood fever at general practice out-of-hours care: an observational cohort study.
Observational study in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02594553 (Optimizing Management and Medication of Febrile Children in Out-of-hours Primary Care), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Management and Medication of Febrile Children in Out-of-hours Primary Care: the CHILI Cluster Randomised Trial
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Clinical Practice Guideline: The Outpatient Management of Fever in Children and Adolescents.Deutsches Arzteblatt international · 2026Guideline
- Antipyretic effect of oral dipyrone (Metamizole) compared to oral ibuprofen in febrile children: a systematic review and meta-analysis.BMC pediatrics · 2024Pooled it
- Randomised comparative trial of the efficacy of paracetamol syrup and dispersible tablets for the treatment of fever in children.The Journal of international medical research · 2021Trial
- Booklet for Childhood Fever in Out-of-Hours Primary Care: A Cluster-Randomized Controlled Trial.Annals of family medicine · 2018Trial
- Trial
- Performance of the Dutch Triage standard in managing fever in children in out-of-hours primary care: a secondary analysis of the chili study.Family practice · 2026Article
- Parents' experiences of telephone nursing when their child has a fever: a mixed method study.BMC nursing · 2026Article
- Article
- Non-malarial etiology of acute febrile episodes in children attending five healthcare facilities in Mwanza, Tanzania years 2020-2021.Scientific reports · 2025Article
- Consensus on the Use of Mefenamic Acid in Pediatric Practice (MAPP): Perspectives From Indian Pediatricians.Cureus · 2025Review
- Article
- The riddle of recurrent fever: a clinical approach to pediatric autoinflammatory diseases.Frontiers in pediatrics · 2024Review
- Over-investigation and overtreatment in pediatrics: a survey from the European Academy of Paediatrics and Japan Pediatric Society.Frontiers in pediatrics · 2024Article
- [Educating Parents about Fever in Childhood Evaluation of the Effect of an Information Leaflet].Klinische Padiatrie · 2023Article
- Approach to fever in children among final-year nursing students: a multicenter survey.BMC nursing · 2023Article
- Adoption of C-reactive protein point-of-care tests for the management of acute childhood infections in primary care in the Netherlands and England: a comparative health systems analysis.BMC health services research · 2023Review
- Article
- Accuracy of parents' subjective assessment of paediatric fever with thermometer measured fever in a primary care setting.BMC primary care · 2022Article
- A scoping review on the use and usefulness of online symptom checkers and triage systems: How to proceed?Frontiers in medicine · 2022Article
- Cross-sectional study of parental knowledge, behaviour and anxiety in management of paediatric fever among German parents.BMJ open · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEven though childhood fever is mostly self-limiting, children with fever constitute a considerable workload in primary care. Little is known about the number of contacts and management during general practitioners' (GPs) out-of-hours care. We investigated all fever related telephone contacts, consultations, antibiotic prescriptions and paediatric referrals of children during GP out-of-hours care within 1 year.
designObservational cohort study. SETTING AND PATIENTS: We performed an observational cohort study at a large Dutch GP out-of-hours service. Children (<12 years) whose parents contacted the GP out-of-hours service for a fever related illness in 2012 were included.
main outcome measuresNumber of contacts and consultations, antibiotic prescription rates and paediatric referral rates.
resultsWe observed an average of 14.6 fever related contacts for children per day at GP out-of-hours services, with peaks during winter months. Of 17,170 contacts in 2012, 5343 (31.1%) were fever related and 70.0% resulted in a GP consultation. One in four consultations resulted in an antibiotic prescription. Prescriptions increased by age and referrals to secondary care decreased by age (p<0.001). The majority of parents (89.5%) contacted the out-of-hours service only once during a fever episode (89.5%) and 7.6% of children were referred to secondary care.
conclusionsThis study shows that childhood fever does account for a large workload at GP out-of-hours services. One in three contacts is fever related and 70% of those febrile children are called in to be assessed by a GP. One in four consultations for childhood fever results in antibiotic prescribing and most consultations are managed in primary care without referral.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.