Evidence map›Paper›PMID 25991064›Full record

ArticleEpidemiology and infection2016

Risk factors for incidence and case-fatality rates of healthcare-associated infections: a 20-year follow-up of a hospital-based cohort.

R-F Wang, S-H Shen, A M-F Yen, T-L Wang, T-N Jang, S-H Lee, J-T Wang, H-H Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R-F WangDivision of Biostatistics,Graduate Institute of Epidemiology and Preventive Medicine,College of Public Health,National Taiwan University,Taipei,Taiwan.
S-H ShenDivision of Biostatistics,Graduate Institute of Epidemiology and Preventive Medicine,College of Public Health,National Taiwan University,Taipei,Taiwan.
A M-F YenDivision of Biostatistics,Graduate Institute of Epidemiology and Preventive Medicine,College of Public Health,National Taiwan University,Taipei,Taiwan.
T-L WangDepartment of Emergency Medicine,Shin Kong Wu Ho-Su Memorial Hospital,Taipei,Taiwan.
T-N JangSchool of Medicine,Fu-Jen Catholic University,New Taipei City,Taiwan.
S-H LeeInfection Control Committee,Shin Kong Wu Ho-Su Memorial Hospital,Taipei,Taiwan.
J-T WangDepartment of Internal Medicine,National Taiwan University Hospital,Taipei,Taiwan.
H-H ChenDivision of Biostatistics,Graduate Institute of Epidemiology and Preventive Medicine,College of Public Health,National Taiwan University,Taipei,Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information is lacking on the integrated evaluation of mortality rates in healthcare-associated infections (HAIs). Our aim was to differentiate the risk factors responsible for the incidence from those for the case-fatality rates in association with HAIs. We therefore examined the time trends of both incidence and case-fatality rates over a 20-year period at a tertiary-care teaching medical centre in Taiwan and the mortality rate was expressed as the product of the incidence rate and the case-fatality rate. During the study period the overall mortality rate fell from 0·46 to 0·32 deaths/1000 patient-days and the incidence rate fell from 3·41 to 2·31/1000 patient-days, but the case-fatality rate increased marginally from 13·5% to 14·0%. The independent risk factors associated with incidence of HAIs were age, gender, infection site, admission type, and department of hospitalization. Significant prognostic factors for HAI case-fatality were age, infection site, intensive care, and clinical department. We conclude that the decreasing trend for the HAI mortality rate was accompanied by a significant decline in the incidence rate and this was offset by a slightly increasing trend in the case-fatality rate. This deconstruction approach could provide further insights into the underlying complex causes of mortality for HAIs.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCross InfectionFemaleFollow-Up StudiesHospitalizationHumansIncidenceInfantInfant, NewbornMaleMiddle AgedCase-fatalityhealthcare-associated infectionincidenceincidence-death cohort

Identifiers

PMID25991064
PMCPMC9507272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.