Evidence map›Paper›PMID 25990738›Full record

ArticleNucleic acids research2015

A low-latency, big database system and browser for storage, querying and visualization of 3D genomic data.

Alexander Butyaev, Ruslan Mavlyutov, Mathieu Blanchette, Philippe Cudré-Mauroux, Jérôme Waldispühl

Abstract readEvaluation Study
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Design Space and Declarative Grammar for 3D Genomic Data Visualization.IEEE transactions on visualization and computer graphics · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Tasks, Techniques, and Tools for Genomic Data Visualization.Computer graphics forum : journal of the European Association for Computer Graphics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexander ButyaevSchool Computer Science, McGill University, Canada.
Ruslan MavlyutoveXascale InfoLab, University of Fribourg, Switzerland.
Mathieu BlanchetteSchool Computer Science, McGill University, Canada.
Philippe Cudré-MaurouxeXascale InfoLab, University of Fribourg, Switzerland phil@exascale.info.
Jérôme WaldispühlSchool Computer Science, McGill University, Canada jeromew@cs.mcgill.ca.

Funding

Canadian Institutes of Health Research P41GM103393
6 · The paper itself

Abstract

Recent releases of genome three-dimensional (3D) structures have the potential to transform our understanding of genomes. Nonetheless, the storage technology and visualization tools need to evolve to offer to the scientific community fast and convenient access to these data. We introduce simultaneously a database system to store and query 3D genomic data (3DBG), and a 3D genome browser to visualize and explore 3D genome structures (3DGB). We benchmark 3DBG against state-of-the-art systems and demonstrate that it is faster than previous solutions, and importantly gracefully scales with the size of data. We also illustrate the usefulness of our 3D genome Web browser to explore human genome structures. The 3D genome browser is available at http://3dgb.cs.mcgill.ca/.

Indexed as

Databases, GeneticGenomicsComputer GraphicsGenesGenes, RetinoblastomaGenome, HumanHumansInternetModels, MolecularPolymorphism, Single Nucleotide

Identifiers

PMID25990738
PMCPMC4652742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.