Evidence map›Paper›PMID 25990632›Full record

ArticleThe European physical journal. E, Soft matter2015

Thermal and inertial resonances in DNA unzipping.

A E Bergues-Pupo, J M Bergues, F Falo, A Fiasconaro

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Article in The European physical journal. E, Soft matter, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

A E Bergues-PupoDepartamento de Física de la Materia Condensada, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain, berguesana@yahoo.es.
J M Bergues
F Falo
A Fiasconaro

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-molecule experiments combined with alternate forces are able to provide useful information not present in standard constant-force and -velocity pulling protocols. Here, we study the effects of such forces in the DNA mechanical unzipping by using an extension of the Peyrard-Bishop-Dauxois model. By changing the damping regime in the dynamical equations, we obtained two resonant mechanisms in both the mean time and the mean force of unzipping. One is thermally assisted and it is characterized by a matching between the period of the external force and the mean unzipping time of the DNA chain, while the other depends on the inertial properties of the system. Both mechanisms are studied systematically under different opening protocols and different parameters of the system. The main results here presented contribute in characterizing and finding optimized conditions in DNA unzipping experiments.

Indexed as

Base PairingModels, TheoreticalBiomechanical PhenomenaDNAHot TemperatureNucleic Acid DenaturationDNA

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.