Evidence map›Paper›PMID 25990620›Full record

ArticleInfection control and hospital epidemiology2015

The Likelihood of Hospital Readmission Among Patients With Hospital-Onset Central Line-Associated Bloodstream Infections.

Carolyn J Khong, James Baggs, David Kleinbaum, Ronda Cochran, John A Jernigan

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Article in Infection control and hospital epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Carolyn J Khong1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
James Baggs1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
David Kleinbaum1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
Ronda Cochran1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
John A Jernigan1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectiveTo determine whether central line-associated bloodstream infections (CLABSIs) increase the likelihood of readmission.

designRetrospective matched cohort study for the years 2008-2009.

settingAcute care hospitals.

participantsMedicare recipients. CLABSI and readmission status were determined by linking National Healthcare Safety Network surveillance data to the Centers for Medicare and Medicaid Services' Medical Provider and Analysis Review in 8 states. Frequency matching was used on International Classification of Diseases, Ninth Revision, Clinical Modification procedure code category and intensive care unit status.

methodsWe compared the rate of readmission among patients with and without CLABSI during an index hospitalization. Cox proportional hazard analysis was used to assess rate of readmission (the first hospitalization within 30 days after index discharge). Multivariate models included the following covariates: race, sex, length of index hospitalization stay, central line procedure code, Gagne comorbidity score, and individual chronic conditions.

resultsOf the 8,097 patients, 2,260 were readmitted within 30 days (27.9%). The rate of first readmission was 7.1 events/person-year for CLABSI patients and 4.3 events/person-year for non-CLABSI patients (P<.001). The final model revealed a small but significant increase in the rate of 30-day readmissions for patients with a CLABSI compared with similar non-CLABSI patients. In the first readmission for CLABSI patients, we also observed an increase in diagnostic categories consistent with CLABSI, including septicemia and complications of a device.

conclusionsOur analysis found a statistically significant association between CLABSI status and readmission, suggesting that CLABSI may have adverse health impact that extends beyond hospital discharge.

Indexed as

AgedAged, 80 and overCatheter-Related InfectionsCentral Venous CathetersCross InfectionFemaleHumansLength of StayMaleMedicarePatient ReadmissionRetrospective StudiesUnited States

Identifiers

PMID25990620
PMCPMC4702248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.