SynthesisParasitology research2015
Onchocerciasis caused by Onchocerca lupi: an emerging zoonotic infection. Systematic review.
Synthesis in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Confirmed cases of human Onchocerca lupi infection: a systematic review of an emerging threat.Parasitology research · 2021Pooled it
- Filarial worms: a systematic review and meta-analysis of diversity in animals from Iran with emphasis on human cases.Parasitology · 2020Pooled it
- Intravitreal Onchocerca sp. With Concomitant Cerebral MRI Lesion: A Case Report.The American journal of case reports · 2026Article
- Prevalence of Onchocerca lupi in shelter dogs from an endemic region of the Southwestern USA.Parasites & vectors · 2025Article
- An investigation of the prevalence of equine filariosis in North and Northeast of Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- Article
- Autochthonous Onchocerca lupi infection of a domestic dog in Austria.Parasites & vectors · 2023Article
- Molecular detection of zoonotic filarioids in Culex spp. from Portugal.Medical and veterinary entomology · 2021Article
- Zoonotic Ocular Onchocercosis byThe Yale journal of biology and medicine · 2021Review
- Efficacy of a spot-on formulation containing moxidectin 2.5%/imidacloprid 10% for the treatment of Cercopithifilaria spp. and Onchocerca lupi microfilariae in naturally infected dogs from Portugal.Parasites & vectors · 2021Article
- Major antigen and paramyosin proteins as candidate biomarkers for serodiagnosis of canine infection by zoonotic Onchocerca lupi.PLoS neglected tropical diseases · 2021Article
- Duplex Real-Time PCR Assay for Clinical Differentiation ofThe American journal of tropical medicine and hygiene · 2020Article
- Zoonotic Implications ofPathogens (Basel, Switzerland) · 2020Review
- Vector-borne nematode diseases in pets and humans in the Mediterranean Basin: An update.Veterinary world · 2019Review
- Linear epitopes in Onchocerca volvulus vaccine candidate proteins and excretory-secretory proteins.Parasite immunology · 2018Article
- Prevalence of intestinal parasites in companion dogs with diarrhea in Beijing, China, and genetic characteristics of Giardia and Cryptosporidium species.Parasitology research · 2018Article
- Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs.PLoS neglected tropical diseases · 2018Article
- Canine ocular onchocerciasis: a retrospective review of the diagnosis, treatment, and outcome of 16 cases in New Mexico (2011-2015).Veterinary ophthalmology · 2017Article
- Onchocerca lupi Nematodes in Dogs Exported from the United States into Canada.Emerging infectious diseases · 2016Article
- First detection of Onchocerca lupi infection in dogs in southern Spain.Parasites & vectors · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Globalization has increased circulation of people, their food, livestock and pets in the world, and changes in the environment, climate and human behaviour have led to the rapid expansion of emerging infections throughout the world. One of the reasons of a new pathogen affecting humans is the passage from an animal to a human being. Onchocerca (O.) lupi, a filarial worm first described in a wolf in 1967, is an emerging pathogen which has been incriminated as the etiological agent for 205 canine, 2 feline and 18 human infections in Europe, Tunisia, Turkey, Iran and the USA. Most frequent findings in animals and humans are monolateral or asymmetrical variably painful subconjunctival swellings and nodules containing immature or mature worms affecting the eye and/or adjacent tissues accompanied by conjunctival hyperemia. Occasionally, subcutaneous nodules and masses affecting the spinal cord have been observed in humans. Diagnosis of O. lupi is achieved by microscopy of excised adult female worms which exhibit a particular cuticular structure and molecular analysis. Treatment consists in worm removal accompanied by antihelminthic, antibiotic and anti-inflammatory therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.