Observational studyInternational journal of colorectal disease2015
Outpatient, non-antibiotic management in acute uncomplicated diverticulitis: a prospective study.
Observational study in International journal of colorectal disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03496090 (Randomized Multicentric Controlled Clinical Trial of Parallel Groups to Evaluate the Non-therapeutic Inferiority of a Free Diet With a Progressive Diet, in the Treatment of Non-complicated Acute Diverticulitis), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Multicentric Controlled Clinical Trial of Parallel Groups to Evaluate the Non-therapeutic Inferiority of a Free Diet With a Progressive Diet, in the Treatment of Non-complicated Acute Diverticulitis
Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Systematic review and meta-analysis of the management of acute uncomplicated diverticulitis: time to change traditional practice.International journal of colorectal disease · 2024Pooled it
- Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Is the outpatient management of acute diverticulitis safe and effective? A systematic review and meta-analysis.Techniques in coloproctology · 2019Pooled it
- Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure.Techniques in coloproctology · 2018Pooled it
- A systematic review and meta-analysis of outpatient treatment for acute diverticulitis.International journal of colorectal disease · 2018Pooled it
- Trial
- Conservative Treatment in Diverticulitis Patients with Pericolic Extraluminal Air and the Role of Antibiotic Treatment.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Trial
- One-day versus four-day antibiotic treatment for acute right colonic uncomplicated diverticulitis: A randomized clinical trial.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Trial
- Multicentre, controlled, randomized clinical trial to compare the efficacy and safety of ambulatory treatment of mild acute diverticulitis without antibiotics with the standard treatment with antibiotics.International journal of colorectal disease · 2017Trial
- Evidence-based clinical practice guidelines for diagnosis and medical management of acute colonic diverticulitis developed by the Korean Association for the Study of Intestinal Diseases (KASID).Intestinal research · 2026Review
- The Emerging Role of the Microbiota and Antibiotics in Diverticulitis Treatment.Clinics in colon and rectal surgery · 2025Review
- A Decade of Follow-Up to Assess the Risk of Recurrence and Surgery after a First Episode of Uncomplicated Left-Sided Diverticulitis.Journal of clinical medicine · 2024Article
- Management of acute uncomplicated diverticulitis and adherence to current guidelines-a multicentre SNAPSHOT study.International journal of colorectal disease · 2024Article
- Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021Review
- Evaluation and Medical Management of Uncomplicated Diverticulitis.Clinics in colon and rectal surgery · 2021Review
- The Bucharest ESTES consensus statement on peritonitis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Review
- [Recommendations for treatment of diverticular disease].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- Observational
- Article
- Current Options for the Emergency Management of Diverticular Disease and Options to Reduce the Need for Colostomy.Clinics in colon and rectal surgery · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to evaluate outpatient, non-antibiotic management in acute uncomplicated diverticulitis with regard to admissions, complications, and recurrences, within a 3-month follow-up period.
methodsA prospective, observational study in which patients with computer tomography-verified acute uncomplicated diverticulitis were managed as outpatients without antibiotics. The patients kept a personal journal, were contacted daily by a nurse, and then followed up by a surgeon at 1 week and 3 months.
resultsIn total, 155 patients were included, of which 54 were men; the mean age of the patients was 57.4 years. At the time of diagnosis, the mean C-reactive protein and white blood cell count were 73 mg/l and 10.5 × 10(9), respectively, and normalized in the vast majority of patients within the first week. The majority of the patients (97.4%) were managed successfully as outpatients without antibiotics, admissions, or complications. In only four (2.6%) patients, the management failed because of complications in three and deterioration in one. These patients were all treated successfully as inpatients without surgery. Five patients had recurrences and were treated as outpatients without antibiotics. Follow-up colonic investigations revealed cancer in two patients and polyps in 13 patients.
conclusionPrevious results of low complication rates with the non-antibiotic policy were confirmed. The new policy of outpatient management without antibiotics in acute uncomplicated diverticulitis is now shown to be feasible, well functioning, and safe.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.