Evidence map›Paper›PMID 25989852›Full record

ArticleBrain structure & function2016

Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits.

Jianping Hu, Dianne Lee, Sien Hu, Sheng Zhang, Herta Chao, Chiang-Shan R Li

Abstract read
In one paragraph

Article in Brain structure & function, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianping HuDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06519, USA.
Dianne LeeDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06519, USA.
Sien HuDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06519, USA.
Sheng ZhangDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06519, USA.
Herta ChaoDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, 06519, USA.
Chiang-Shan R LiDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06519, USA. chiang-shan.li@yale.edu.

Funding

Cognitive control and cocaine dependence: thalamic noradrenergic processesR01DA023248 · NIDA · YALE UNIVERSITY · PI LI, CHIANG-SHAN RAY · 2008 to 2018
$4.0M
Cerebral Correlates of Early Habitual DrinkingR01AA021449 · NIAAA · YALE UNIVERSITY · PI LI, CHIANG-SHAN RAY · 2013 to 2017
$1.2M
Imaging Cognitive Control in Cocaine DependenceK02DA026990 · NIDA · YALE UNIVERSITY · PI LI, CHIANG-SHAN RAY · 2009 to 2013
$639k
NIAAA NIH HHS R01 AA021449NIDA NIH HHS K02 DA026990NIDA NIH HHS R01 DA023248
6 · The paper itself

Abstract

Personality traits contribute to variation in human behavior, including the propensity to take risk. Extant work targeted risk-taking processes with an explicit manipulation of reward, but it remains unclear whether personality traits influence simple decisions such as speeded versus delayed responses during cognitive control. We explored this issue in an fMRI study of the stop signal task, in which participants varied in response time trial by trial, speeding up and risking a stop error or slowing down to avoid errors. Regional brain activations to speeded versus delayed motor responses (risk-taking) were correlated to novelty seeking (NS), harm avoidance (HA) and reward dependence (RD), with age and gender as covariates, in a whole brain regression. At a corrected threshold, the results showed a positive correlation between NS and risk-taking responses in the dorsomedial prefrontal, bilateral orbitofrontal, and frontopolar cortex, and between HA and risk-taking responses in the parahippocampal gyrus and putamen. No regional activations varied with RD. These findings demonstrate that personality traits influence the neural processes of executive control beyond behavioral tasks that involve explicit monetary reward. The results also speak broadly to the importance of characterizing inter-subject variation in studies of cognition and brain functions.

Indexed as

IndividualityMotor ActivityAdultAvoidance LearningBrainBrain MappingDecision MakingExecutive FunctionExploratory BehaviorFemaleFrontal LobeHumansMagnetic Resonance ImagingMaleRisk-TakingYoung AdultAnxietyImpulsivityNo-goReaction timeTPQ

Identifiers

PMID25989852
PMCPMC4654717

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.