Evidence map›Paper›PMID 25989440›Full record

ArticleScientific reports2015

An embryo of protocells: The capsule of graphene with selective ion channels.

Zhan Li, Chunmei Wang, Longlong Tian, Jing Bai, Huijun Yao, Yang Zhao, Xin Zhang, Shiwei Cao, Wei Qi, Suomin Wang and 9 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Zhan Li1] Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China [2] Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Chunmei WangLanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou, 730050, P.R. China.
Longlong TianRadiochemistry Laboratory, Lanzhou University, Lanzhou, 730000, P.R. China.
Jing BaiInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Huijun YaoInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Yang Zhao1] Department of Chemistry, State Key Lab of Molecular Engineering of Polymers, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, and Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200433, P. R. China [2] School of Nuclear Science and Technology, Lanzhou University, Lanzhou, 730000, P.R. China.
Xin ZhangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Shiwei CaoInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Wei QiRadiochemistry Laboratory, Lanzhou University, Lanzhou, 730000, P.R. China.
Suomin WangState Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730000, P.R. China.
Keliang ShiRadiochemistry Laboratory, Lanzhou University, Lanzhou, 730000, P.R. China.
Youwen XuBrookhaven National Laboratory Medical Department, Building 901, Room 106, Upton, NY 11973.
Zhang MingliangKey Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Bo LiuRadiochemistry Laboratory, Lanzhou University, Lanzhou, 730000, P.R. China.
Hongdeng QiuKey Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Jie LiuInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, P.R. China.
Wangsuo WuRadiochemistry Laboratory, Lanzhou University, Lanzhou, 730000, P.R. China.
Xiaoli WangLanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou, 730050, P.R. China.
An WenzhenSchool of life science, Lanzhou University, Lanzhou, 730000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of artificial cell is a route for searching the origin of protocell. Here, we create a novel cell model of graphene capsules with selective ion channels, indicating that graphene might be an embryo of protocell membrane. Firstly, we found that the highly oxidized graphene and phospholipid-graphene oxide composite would curl into capsules under a strongly acidic saturated solution of heavy metallic salt solution at low temperature. Secondly, L-amino acids exhibited higher reactivity than D-amino acids on graphene oxides to form peptides, and the formed peptides in the influence of graphene would be transformed into a secondary structure, promoting the formation of left-handed proteins. Lastly, monolayer nanoporous graphene, prepared by unfocused (84)Kr(25+), has a high selectivity for permeation of the monovalent metal ions ( Rb(+) > K(+) > Cs(+) > Na(+) > Li(+), based on permeation concentration), but does not allow Cl(-) go through. It is similar to K(+) channels, which would cause an influx of K(+) into capsule of graphene with the increase of pH in the primitive ocean, creating a suitable inner condition for the origin of life. Therefore, we built a model cell of graphene, which would provide a route for reproducing the origin of life.

Indexed as

Amino AcidsArtificial CellsCations, MonovalentGraphiteIon ChannelsMetals, HeavyOxidesAmino AcidsCations, MonovalentGraphiteIon ChannelsMetals, HeavyOxides

Identifiers

PMID25989440
PMCPMC4437305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.