Evidence map›Paper›PMID 25988708›Full record

Trial reportAlcoholism, clinical and experimental research2015

Using Transdermal Alcohol Monitoring to Detect Low-Level Drinking.

John D Roache, Tara E Karns, Nathalie Hill-Kapturczak, Jillian Mullen, Yuanyuan Liang, Richard J Lamb, Donald M Dougherty

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Alcoholism, clinical and experimental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Accuracy of transdermal alcohol monitoring devices in a laboratory setting.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. CRIMINAL DETERRENCE: EVIDENCE FROM AN INDIVIDUAL-LEVEL ANALYSIS OF 24/7 SOBRIETY.Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management] · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

John D RoacheDepartment of Psychiatry , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Tara E KarnsDepartment of Psychiatry , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Nathalie Hill-KapturczakDepartment of Psychiatry , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Jillian MullenDepartment of Psychiatry , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Yuanyuan LiangDepartment of Epidemiology and Biostatistics , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Richard J LambDepartment of Psychiatry , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Donald M DoughertyDepartment of Psychiatry , The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
The University of Texas Health Science Center at San Antonio · US

Funding

Leveraging Transdermal Alcohol Monitoring to Reduce Drinking among DWI DefendantsR01AA014988 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DOUGHERTY, DONALD M, HILL-KAPTURCZAK, NATHALIE · 2005 to 2021
$8.6M
Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2M
NIAAA NIH HHS R01 AA014988NIAAA NIH HHS R01AA14988NIDA NIH HHS T32 DA031115NIDA NIH HHS T32DA031115
6 · The paper itself

Abstract

backgroundSeveral studies demonstrate the utility of Alcohol Monitoring Systems' (AMS) transdermal alcohol concentration (TAC) monitor to objectively quantify drinking. AMS standard criteria (i.e., TAC >0.02 g/dl) used for drinking detection are deliberately conservative, but consequently only detect drinking equivalent to 5 or more standard drinks. Our study sought to characterize the sensitivity of TAC measurement to detect low-level drinking defined as the consumption of 1 to 3 beers.

methodsData were pooled from 3 studies giving controlled doses of 1, 2, 3, 4, and 5 Corona© beers (12 oz = 0.92 standard units) to 32 male and 29 female research volunteers wearing TAC monitors under controlled conditions. Analyses describe the sensitivity to detect drinking at various peak TAC thresholds beginning with any positive reading >0 g/dl, and then using TAC thresholds of 0.02 and 0.03 g/dl.

resultsNearly 40% of participants drinking 1 beer did not have a positive TAC reading. However, positive TAC readings were observed in more than 95 and in 100% of participants drinking 2 and 3 or more beers, respectively. The probability of peak TAC detection was a positive function of the number of beers consumed and a negative function of the minimum TAC threshold for detection. Drinking was somewhat more likely to be detected in females than males drinking 2 to 5 beers, but not after 1 beer. Use of AMS standard criteria only reliably detected the consumption of 5 beers, and 45.9% of all occasions of drinking 1 to 3 beers were undetected using 0.02 g/dl as a threshold.

conclusionsPeak TAC levels between 0 and 0.02 g/dl must be considered to detect the low-level drinking of 1 to 3 standard drinks, and such thresholds are necessary when researchers and clinicians want to detect low-level drinking.

Indexed as

Alcohol DrinkingAdultBreath TestsDrug MonitoringEthanolFemaleHealthy VolunteersHumansMaleMiddle AgedSkinYoung AdultEthanolAlcohol ConsumptionHeavy DrinkingLow-Level DrinkingTransdermal Alcohol ConcentrationTransdermal Alcohol Monitoring

Identifiers

PMID25988708
PMCPMC4490934
OpenAlexW1950055679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.