Evidence map›Paper›PMID 25988315›Full record

ArticleScientific reports2015

ImmuSort, a database on gene plasticity and electronic sorting for immune cells.

Pingzhang Wang, Yehong Yang, Wenling Han, Dalong Ma

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pingzhang Wang1] Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center. Key Laboratory of Medical Immunology, Ministry of Health, China. Peking University Center for Human Disease Genomics. No. 38 Xueyuan Road, Beijing, 100191, China [2] Chinese National Human Genome Center at Beijing. No. 3-707 North YongChang Road, BDA, Beijing, 100176, China.
Yehong YangTip-Science(Beijing) Bioinformatics Co. Ltd. The current affiliation: Institute of Basic Medical Sciences Chinese Academy of Medical Sciences. No. 5 Dong Dan San Tiao, Beijing, 10005, China.
Wenling HanDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center. Key Laboratory of Medical Immunology, Ministry of Health, China. Peking University Center for Human Disease Genomics. No. 38 Xueyuan Road, Beijing, 100191, China.
Dalong MaDepartment of Immunology, School of Basic Medical Sciences, Peking University Health Science Center. Key Laboratory of Medical Immunology, Ministry of Health, China. Peking University Center for Human Disease Genomics. No. 38 Xueyuan Road, Beijing, 100191, China.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene expression is highly dynamic and plastic. We present a new immunological database, ImmuSort. Unlike other gene expression databases, ImmuSort provides a convenient way to view global differential gene expression data across thousands of experimental conditions in immune cells. It enables electronic sorting, which is a bioinformatics process to retrieve cell states associated with specific experimental conditions that are mainly based on gene expression intensity. A comparison of gene expression profiles reveals other applications, such as the evaluation of immune cell biomarkers and cell subsets, identification of cell specific and/or disease-associated genes or transcripts, comparison of gene expression in different transcript variants and probe set quality evaluation. A plasticity score is introduced to measure gene plasticity. Average rank and marker evaluation scores are used to evaluate biomarkers. The current version includes 31 human and 17 mouse immune cell groups, comprising 10,422 and 3,929 microarrays derived from public databases, respectively. A total of 20,283 human and 20,963 mouse genes are available to query in the database. Examples show the distinct advantages of the database. The database URL is http://202.85.212.211/Account/ImmuSort.html.

Indexed as

Databases, GeneticAlgorithmsAnimalsBiomarkersCell PlasticityGene Expression ProfilingHumansInternetMiceOligonucleotide Array Sequence AnalysisTranscriptomeBiomarkers

Identifiers

PMID25988315
PMCPMC4437374
OpenAlexW2272159258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.