ArticleNeuroImage2015
The aging brain shows less flexible reallocation of cognitive resources during dual-task walking: A mobile brain/body imaging (MoBI) study.
Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Preprocessing choices for P3 analyses with mobile EEG: A systematic literature review and interactive exploration.Psychophysiology · 2025Pooled it
- Experiment protocols for brain-body imaging of locomotion: A systematic review.Frontiers in neuroscience · 2023Pooled it
- Brain activity during dual task gait and balance in aging and age-related neurodegenerative conditions: A systematic review.Experimental gerontology · 2019Pooled it
- Placebo effect on gait: a way to reduce the dual-task cost in older adults.Experimental brain research · 2023Trial
- The Characteristics of the Reduction of Interference Effect during Dual-Task Cognitive-Motor Training Compared to a Single Task Cognitive and Motor Training in Elderly: A Randomized Controlled Trial.International journal of environmental research and public health · 2023Trial
- The Effect of Two Different Cognitive Tests on Gait Parameters during Dual Tasks in Healthy Postmenopausal Women.BioMed research international · 2016Trial
- Age-related changes in sustained visual attentional modulation of audiovisual integration.Attention, perception & psychophysics · 2026Article
- Neural signatures of dual-task walking demands in individuals at risk of cognitive impairment.npj aging · 2026Article
- [Gait characteristics in patients with persistent postural-perceptual dizziness].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Article
- A symphony of functioning: exploring the interplay of cognition, movement, and visual demands in adolescents on the autism spectrum using mobile brain-body imaging (MoBI).Journal of neurodevelopmental disorders · 2026Article
- Feasibility and preliminary effects of non-immersive virtual reality motor-cognitive treadmill training in older Veterans: a single-arm pilot study.BMC geriatrics · 2026Article
- The association between mobility and a cognitive measure of attention and processing speed in middle-aged adults: a cross-sectional study.Scientific reports · 2025Article
- Walking Modulates Active Auditory Sensing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A symphony of functioning: Assessing the interplay of cognition, movement, and visual processing in adolescents on the autism spectrum using mobile brain-body imaging (MoBI).Research square · 2025Article
- Article
- Linking Dementia Pathology and Alteration in Brain Activation to Complex Daily Functional Decline During the Preclinical Dementia Stages: Protocol for a Prospective Observational Cohort Study.JMIR research protocols · 2024Observational
- Reduced Proactive and Reactive Cognitive Flexibility in Older Adults Underlies Performance Costs During Dual-Task Walking: A Mobile Brain/Body Imaging (MoBI) Study.bioRxiv : the preprint server for biology · 2024Article
- Striatal Acetylcholine and Dopamine Interactions Produce Situationappropriate Action Selection.Current neuropharmacology · 2024Review
- Repeated multi-domain cognitive training prevents cognitive decline, anxiety and amyloid pathology found in a mouse model of Alzheimer disease.Communications biology · 2023Article
- Maintaining Task Performance Levels Under Cognitive Load While Walking Requires Widespread Reallocation of Neural Resources.Neuroscience · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Aging is associated with reduced abilities to selectively allocate attention across multiple domains. This may be particularly problematic during everyday multitasking situations when cognitively demanding tasks are performed while walking. Due to previous limitations in neuroimaging technology, much remains unknown about the cortical mechanisms underlying resource allocation during locomotion. Here, we utilized an EEG-based mobile brain/body imaging (MoBI) technique that integrates high-density event-related potential (ERP) recordings with simultaneously acquired foot-force sensor data to monitor gait patterns and brain activity concurrently. To assess effects of motor load on cognition we evaluated young (N=17; mean age=27.2) and older adults (N=16; mean age=63.9) and compared behavioral and ERP measures associated with performing a Go/No-Go response inhibition task as participants sat stationary or walked on a treadmill. Stride time and variability were also measured during task performance and compared to stride parameters obtained without task performance, thereby assessing effects of cognitive load on gait. Results showed that older, but not young adults' accuracy dropped significantly when performing the inhibitory task while walking. Young adults revealed ERP modulations at relatively early (N2 amplitude reduction) and later (earlier P3 latency) stages within the processing stream as motor load increased while walking. In contrast, older adults' ERP modulations were limited to later processing stages (increased P3 amplitude) of the inhibitory network. The relative delay and attenuation of ERP modulations accompanied by behavioral costs in older participants might indicate an age-associated loss in flexible resource allocation across multiple tasks. Better understanding of the neural underpinnings of these age-related changes may lead to improved strategies to reduce fall risk and enhance mobility in aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.