Evidence map›Paper›PMID 25988189›Full record

ArticleACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine

Integrated miRNA and mRNA Analysis of Time Series Microarray Data.

Julian Dymacek, Nancy Lan Guo

Abstract read
In one paragraph

Article in ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julian DymacekMary Babb Randolph Cancer Center West Virginia University Morgantown, WV 26506, USA jdymacek@mix.wvu.edu.
Nancy Lan GuoMary Babb Randolph Cancer Center West Virginia University Morgantown, WV 26506, USA lguo@hsc.wvu.edu.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI JUDITH FEINBERG · 2012 to 2026
$81.0M
Systematic assessment of multi-walled carbon nanotubes in pulmonary diseaseR01ES021764 · NIEHS · WEST VIRGINIA UNIVERSITY · PI GUO, NANCY LAN · 2012 to 2016
$1.7M
A Novel Computational Framework for individualized clinical decision-makingR56LM009500 · NLM · WEST VIRGINIA UNIVERSITY · PI GUO, NANCY LAN · 2012 to 2013
$499k
NIEHS NIH HHS R01 ES021764NIGMS NIH HHS U54 GM104942NLM NIH HHS R56 LM009500
6 · The paper itself

Abstract

The dynamic temporal regulatory effects of microRNA are not well known. We introduce a technique for integrating miRNA and mRNA time series microarray data with known disease pathology. The integrated analysis includes identifying both mRNA and miRNA that are signi cantly similar to the quantitative pathology. Potential regulatory miRNA/mRNA target pairs are identi ed through databases of both predicted and validated pairs. Finally, potential target pairs are ltered by examining the second derivatives of the fold changes over time. Our system was used on genome-wide microarray expression data of mouse lungs (

Identifiers

PMID25988189
PMCPMC4433490

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.